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1
ERP Mismatch Negativity Amplitude and Asymmetry Reflect Phonological and Rapid Automatized Naming Skills in English-Speaking Kindergartners
In: Frontiers (2021)
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2
Putative protective neural mechanisms in prereaders with a family history of dyslexia who subsequently develop typical reading skills
In: Wiley (2021)
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3
Putative protective neural mechanisms in prereaders with a family history of dyslexia who subsequently develop typical reading skills
In: Wiley (2021)
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4
Putative protective neural mechanisms in prereaders with a family history of dyslexia who subsequently develop typical reading skills
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5
Putative protective neural mechanisms in prereaders with a family history of dyslexia who subsequently develop typical reading skills
In: Hum Brain Mapp (2020)
Abstract: Developmental dyslexia affects 40–60% of children with a familial risk (FHD+) compared to a general prevalence of 5–10%. Despite the increased risk, about half of FHD+ children develop typical reading abilities (FHD+Typical). Yet the underlying neural characteristics of favorable reading outcomes in at‐risk children remain unknown. Utilizing a retrospective, longitudinal approach, this study examined whether putative protective neural mechanisms can be observed in FHD+Typical at the prereading stage. Functional and structural brain characteristics were examined in 47 FHD+ prereaders who subsequently developed typical (n = 35) or impaired (n = 12) reading abilities and 34 controls (FHD−Typical). Searchlight‐based multivariate pattern analyses identified distinct activation patterns during phonological processing between FHD+Typical and FHD−Typical in right inferior frontal gyrus (RIFG) and left temporo‐parietal cortex (LTPC) regions. Follow‐up analyses on group‐specific classification patterns demonstrated LTPC hypoactivation in FHD+Typical compared to FHD−Typical, suggesting this neural characteristic as an FHD+ phenotype. In contrast, RIFG showed hyperactivation in FHD+Typical than FHD−Typical, and its activation pattern was positively correlated with subsequent reading abilities in FHD+ but not controls (FHD−Typical). RIFG hyperactivation in FHD+Typical was further associated with increased interhemispheric functional and structural connectivity. These results suggest that some protective neural mechanisms are already established in FHD+Typical prereaders supporting their typical reading development.
Keyword: Research Articles
URL: http://www.ncbi.nlm.nih.gov/pubmed/32166830
https://doi.org/10.1002/hbm.24980
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294063/
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6
Understanding Event-Related Potentials (ERPs) in Clinical and Basic Language and Communication Disorders Research: A Tutorial
In: Int J Lang Commun Disord (2020)
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7
Taking Language Samples Home: Feasibility, Reliability, and Validity of Child Language Samples Conducted Remotely With Video Chat Versus In-Person
In: J Speech Lang Hear Res (2020)
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8
Language processing skills linked to FMR1 variation: A study of gaze-language coordination during rapid automatized naming among women with the FMR1 premutation
Nayar, Kritika; McKinney, Walker; Hogan, Abigail L.. - : Public Library of Science, 2020
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9
Language processing skills linked to FMR1 variation: A study of gaze-language coordination during rapid automatized naming among women with the FMR1 premutation
Nayar, Kritika; McKinney, Walker; Hogan, Abigail L.. - : Public Library of Science, 2019
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10
Talking Tots and the Terrible Twos: Early Language and Disruptive Behavior in Toddlers
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11
Functional neuroanatomical evidence for the double-deficit hypothesis of developmental dyslexia.
Norton, Elizabeth S; Black, Jessica M; Stanley, Leanne M. - : eScholarship, University of California, 2014
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12
Tracking the Roots of Reading Ability: White Matter Volume and Integrity Correlate with Phonological Awareness in Prereading and Early-Reading Kindergarten Children
Saygin, Zeynep M.; Norton, Elizabeth S.; Osher, David E.. - : Society for Neuroscience, 2013
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13
Brain Basis of Phonological Awareness for Spoken Language in Children and Its Disruption in Dyslexia
Kovelman, Ioulia; Norton, Elizabeth S.; Christodoulou, Joanna A.. - : Oxford University Press, 2012
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14
Brain Basis of Phonological Awareness for Spoken Language in Children and Its Disruption in Dyslexia
Kovelman, Ioulia; Norton, Elizabeth S.; Christodoulou, Joanna A.. - : Oxford University Press, 2012
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15
Brain Basis of Phonological Awareness for Spoken Language in Children and Its Disruption in Dyslexia
Kovelman, Ioulia; Norton, Elizabeth S.; Christodoulou, Joanna A.. - : Oxford University Press, 2011
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16
Are There Separate Neural Systems for Spelling? New Insights into the Role of Rules and Memory in Spelling from Functional Magnetic Resonance Imaging
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