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Developing, monitoring, and reporting of fidelity in aphasia trials: Core recommendations from the collaboration of aphasia trialists (CATs) trials for aphasia panel
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In: Research outputs 2022 to 2026 (2022)
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Functional Connectivity and Speech Entrainment Speech Entrainment Improves Connectivity Between Anterior and Posterior Cortical Speech Areas in Non-fluent Aphasia ...
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Functional Connectivity and Speech Entrainment Speech Entrainment Improves Connectivity Between Anterior and Posterior Cortical Speech Areas in Non-fluent Aphasia ...
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Speech Entrainment Improves Connectivity Between Anterior and Posterior Cortical Speech Areas in Non-Fluent Aphasia
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In: Neurorehabil Neural Repair (2022)
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Neural correlates of impaired vocal feedback control in post-stroke aphasia
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In: Neuroimage (2022)
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Abstract:
We used left-hemisphere stroke as a model to examine how damage to sensorimotor brain networks impairs vocal auditory feedback processing and control. Individuals with post-stroke aphasia and matched neurotypical control subjects vocalized speech vowel sounds and listened to the playback of their self-produced vocalizations under normal (NAF) and pitch-shifted altered auditory feedback (AAF) while their brain activity was recorded using electroencephalography (EEG) signals. Event-related potentials (ERPs) were utilized as a neural index to probe the effect of vocal production on auditory feedback processing with high temporal resolution, while lesion data in the stroke group was used to determine how brain abnormality accounted for the impairment of such mechanisms. Results revealed that ERP activity was aberrantly modulated during vocalization vs. listening in aphasia, and this effect was accompanied by the reduced magnitude of compensatory vocal responses to pitch-shift alterations in the auditory feedback compared with control subjects. Lesion-mapping revealed that the aberrant pattern of ERP modulation in response to NAF was accounted for by damage to sensorimotor networks within the left-hemisphere inferior frontal, precentral, inferior parietal, and superior temporal cortices. For responses to AAF, neural deficits were predicted by damage to a distinguishable network within the inferior frontal and parietal cortices. These findings define the left-hemisphere sensorimotor networks implicated in auditory feedback processing, error detection, and vocal motor control. Our results provide translational synergy to inform the theoretical models of sensorimotor integration while having clinical applications for diagnosis and treatment of communication disabilities in individuals with stroke and other neurological conditions.
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URL: http://www.ncbi.nlm.nih.gov/pubmed/35092839 https://doi.org/10.1016/j.neuroimage.2022.118938 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920755/
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Functional differentiation in the language network revealed by lesion-symptom mapping
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In: Neuroimage (2022)
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sj-docx-1-nnr-10.1177_1545968321999052 – Supplemental material for Indirect White Matter Pathways Are Associated With Treated Naming Improvement in Aphasia ...
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Indirect White Matter Pathways Are Associated With Treated Naming Improvement in Aphasia ...
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Indirect White Matter Pathways Are Associated With Treated Naming Improvement in Aphasia ...
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Measuring change in picture naming ability (Walker et al., 2021) ...
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sj-docx-1-nnr-10.1177_1545968321999052 – Supplemental material for Indirect White Matter Pathways Are Associated With Treated Naming Improvement in Aphasia ...
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Measuring change in picture naming ability (Walker et al., 2021) ...
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Cortical microstructural changes associated with treated aphasia recovery
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In: Ann Clin Transl Neurol (2021)
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Isolating the white matter circuitry of the dorsal language stream: Connectome‐Symptom Mapping in stroke induced aphasia
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In: Hum Brain Mapp (2021)
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Protocol for Escitalopram and Language Intervention for Subacute Aphasia (ELISA): A randomized, double blind, placebo-controlled trial
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In: PLoS One (2021)
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Independent contributions of structural and functional connectivity: Evidence from a stroke model
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In: Netw Neurosci (2021)
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One cat, Two cats, Red cat, Blue cats: Eliciting morphemes from individuals with primary progressive aphasia.
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In: Aphasiology (2021)
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Current Approaches to the Treatment of Post-Stroke Aphasia
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In: J Stroke (2021)
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Indirect white matter pathways are associated with treated naming improvement in aphasia
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In: Neurorehabil Neural Repair (2021)
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2018 ASHA Research Symposium: Julius Fridricksson, BDNF Genotype & Brain Activation in Aphasia ...
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