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Dynamic functional brain network connectivity during pseudoword processing relates to children’s reading skill
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Providing a parent-administered outcome measure in a bilingual family of a father and a mother of two adolescents with ASD: brief report.
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In: Developmental neurorehabilitation, vol 25, iss 2 (2022)
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"You used 'elle,' so now you're a girl": Discursive possibilities for a non-binary teenager in French class
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In: L2 Journal, vol 14, iss 3 (2022)
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Developmental screening using caregiver report: an evaluation of screening tools and childhood developmental delays in South Africa ...
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Developmental screening using caregiver report: an evaluation of screening tools and childhood developmental delays in South Africa ...
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Gender Does Not Equal Genitalia: A Review of the Implications of Inclusivity in School-Based Sexual Health Education on the Identity Development of Non-Binary and Transgender Adolescents
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In: University Honors Theses (2022)
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Moving from Needs Assessment to Intervention: Fathers’ Perspectives on Their Needs and Support for Talk with Teens about Sex
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In: International Journal of Environmental Research and Public Health; Volume 19; Issue 6; Pages: 3315 (2022)
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The Psychometric Properties and Cutoff Score of the Child and Adolescent Mindfulness Measure (CAMM) in Chinese Primary School Students
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In: Children; Volume 9; Issue 4; Pages: 499 (2022)
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Engaging Disinterested Adolescent Readers in the Middle School Classroom
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In: Culminating Experience Projects (2022)
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Psychological Interventions for Pediatric Headache Disorders: A 2021 Update on Research Progress and Needs
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In: Curr Pain Headache Rep (2022)
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Still connecting the dots : an investigation into infants' attentional bias to threat using an eye-tracking task
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Motivating the unmotivated: A self-study about engaging adolescent readers to read for joy before and during a pandemic
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Emerging themes in the development of prospective memory during childhood
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| 14 |
Drug induced stuttering: pharmacovigilance data ; Drug induced stuttering: pharmacovigilance data.
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In: ISSN: 1474-0338 ; EISSN: 1744-764X ; Expert Opinion on Drug Safety ; https://hal.archives-ouvertes.fr/hal-03474488 ; Expert Opinion on Drug Safety, Informa Healthcare, 2021, 20 (3), pp.373-378. ⟨10.1080/14740338.2021.1867101⟩ (2021)
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| 15 |
Effect Sizes of Deletions and Duplications on Autism Risk Across the Genome
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Douard, Elise; Zeribi, Abderrahim; Schramm, Catherine; Tamer, Petra; Loum, Mor Absa; Nowak, Sabrina; Saci, Zohra; Lord, Marie-Pier; Rodríguez-Herreros, Borja; Jean-Louis, Martineau; Moreau, Clara; Loth, Eva; Schumann, Gunter; Pausova, Zdenka; Elsabbagh, Mayada; Almasy, Laura; Glahn, David,; Bourgeron, Thomas; Labbe, Aurélie; Paus, Tomas; Mottron, Laurent; Greenwood, Celia,; Huguet, Guillaume; Jacquemont, Sébastien
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In: ISSN: 0002-953X ; EISSN: 1535-7228 ; American Journal of Psychiatry ; https://hal-pasteur.archives-ouvertes.fr/pasteur-03325371 ; American Journal of Psychiatry, American Psychiatric Publishing, 2021, 178 (1), pp.87-98. ⟨10.1176/appi.ajp.2020.19080834⟩ (2021)
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Abstract:
International audience ; Objective:Deleterious copy number variants (CNVs) are identified in up to 20% of individuals with autism. However, levels of autism risk conferred by most rare CNVs remain unknown. The authors recently developed statistical models to estimate the effect size on IQ of all CNVs, including undocumented ones. In this study, the authors extended this model to autism susceptibility.Methods:The authors identified CNVs in two autism populations (Simons Simplex Collection and MSSNG) and two unselected populations (IMAGEN and Saguenay Youth Study). Statistical models were used to test nine quantitative variables associated with genes encompassed in CNVs to explain their effects on IQ, autism susceptibility, and behavioral domains.Results:The “probability of being loss-of-function intolerant” (pLI) best explains the effect of CNVs on IQ and autism risk. Deleting 1 point of pLI decreases IQ by 2.6 points in autism and unselected populations. The effect of duplications on IQ is threefold smaller. Autism susceptibility increases when deleting or duplicating any point of pLI. This is true for individuals with high or low IQ and after removing de novo and known recurrent neuropsychiatric CNVs. When CNV effects on IQ are accounted for, autism susceptibility remains mostly unchanged for duplications but decreases for deletions. Model estimates for autism risk overlap with previously published observations. Deletions and duplications differentially affect social communication, behavior, and phonological memory, whereas both equally affect motor skills.Conclusions:Autism risk conferred by duplications is less influenced by IQ compared with deletions. The model applied in this study, trained on CNVs encompassing >4,500 genes, suggests highly polygenic properties of gene dosage with respect to autism risk and IQ loss. These models will help to interpret CNVs identified in the clinic.
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Keyword:
[SCCO.NEUR]Cognitive science/Neuroscience; Autism Spectrum Disorder; Copy Number Variants; IQ; MESH: Adolescent; MESH: Adult; MESH: Autistic Disorder; MESH: Case-Control Studies; MESH: Child; MESH: DNA Copy Number Variations; MESH: Female; MESH: Gene Deletion; MESH: Gene Duplication; MESH: Genetic Predisposition to Disease; MESH: Genome; MESH: Humans; MESH: Intelligence; MESH: Male; MESH: Risk Factors
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URL: https://doi.org/10.1176/appi.ajp.2020.19080834
https://hal-pasteur.archives-ouvertes.fr/pasteur-03325371
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| 16 |
Sí Se Puede, Sí Se Pudo, Sí Se Va a Poder: The Narrative Experience of Newcomer Immigrant Adolescent Students in Obtaining a High School Diploma
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| 17 |
Structural Inequities and the Impact of COVID-19 on Latinx Children: Implications for Child and Adolescent Mental Health Practice.
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In: Journal of the American Academy of Child and Adolescent Psychiatry, vol 60, iss 6 (2021)
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A systematic review of cognitive behavior therapy and dialectical behavior therapy for adolescent eating disorders.
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In: Journal of eating disorders, vol 9, iss 1 (2021)
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Social Functioning as a Mediator between Developmental Language Disorder (DLD) and Emotional Problems in Adolescents. ...
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“Do environmental contaminant substances have potential negative effect on children´s speech, language, and communication? A systematic review” ...
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