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Neurolinguist am Aachener Klinikum. Gespräch mit Prof. Dr. Walter Huber
Huber, Walter [Verfasser]. - 2019
DNB Subject Category Language
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2
Training-related changes of brain activation for speech production in healthy speakers - a longitudinal fMRI study to mimic aphasia therapy
Huber, Walter; Willmes, Klaus; Meyer, Corinna Maria. - : ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, 2017
BASE
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3
Determinants of Concurrent Motor and Language Recovery during Intensive Therapy in Chronic Stroke Patients: Four Single-Case Studies.
BASE
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4
Therapy-induced brain reorganization patterns in aphasia
In: Brain. - 138, 4 (2015) , 1097-1112, ISSN: 1460-2156 (2015)
BASE
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5
The direction of word stress processing in German: evidence from a working memory paradigm
Domahs, Frank [Verfasser]; Grande, Marion [Verfasser]; Huber, Walter [Verfasser]. - Aachen : Universitätsbibliothek der RWTH Aachen, 2014
DNB Subject Category Language
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6
Eye movement analyses indicate the underlying reading strategy in the recovery of lexical readers
In: Aphasiology. - London [u.a.] : Routledge, Taylor & Francis Group 28 (2014) 6, 640-657
OLC Linguistik
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7
Longitudinal changes in brains of patients with fluent primary progressive aphasia
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 131 (2014), 11-19
OLC Linguistik
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8
The direction of word stress processing in German: evidence from a working memory paradigm
Domahs, Frank; Grande, Marion; Huber, Walter. - : Frontiers Media S.A., 2014
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9
Paving the Way for Speech: Voice-Training-Induced Plasticity in Chronic Aphasia and Apraxia of Speech—Three Single Cases
Jungblut, Monika; Huber, Walter; Mais, Christiane. - : Hindawi Publishing Corporation, 2014
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10
The neural correlates of agrammatism: Evidence from aphasic and healthy speakers performing an overt picture description task
Schönberger, Eva; Heim, Stefan; Meffert, Elisabeth. - : Frontiers Media S.A., 2014
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11
Good, bad and ugly word stress – fMRI evidence for foot structure driven processing of prosodic violations
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 125 (2013) 3, 272-282
OLC Linguistik
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12
Effects of lexicality and word frequency on brain activation in dyslexic readers
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 125 (2013) 2, 194-202
OLC Linguistik
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13
Construct validity of modified time-interval analysis in measuring stuttering and trained speaking patterns
In: Journal of fluency disorders. - New York, NY : Elsevier 37 (2012) 1, 42-53
BLLDB
OLC Linguistik
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14
Tobias Haug: Adaptation and evaluation of a German Sign Language test [Rezension]
In: Das Zeichen. - Hamburg : Gesellschaft für Gebärdensprache und Kommunikation Gehörloser e.V. 26 (2012) 90, 194-202
BLLDB
OLC Linguistik
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15
Computer-assisted analysis of spontaneous speech: quantification of basic parameters in aphasic and unimpaired language
In: Clinical linguistics & phonetics. - London : Informa Healthcare 26 (2012) 8, 661-680
BLLDB
OLC Linguistik
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16
The Role of Human Parietal Area 7A as a Link between Sequencing in Hand Actions and in Overt Speech Production ...
Heim, Stefan; Amunts, Katrin; Hensel, Tanja. - : RWTH Aachen University, 2012
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17
Enhancement and suppression in a lexical interference fMRI-paradigm ...
Abel, Stefanie; Dressel, Katharina; Weiller, Cornelius. - : RWTH Aachen University, 2012
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18
The Role of Human Parietal Area 7A as a Link between Sequencing in Hand Actions and in Overt Speech Production
Heim, Stefan; Amunts, Katrin; Hensel, Tanja. - : Frontiers Media S.A., 2012
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19
Enhancement and suppression in a lexical interference fMRI-paradigm
Abel, Stefanie; Dressel, Katharina; Weiller, Cornelius; Huber, Walter. - : Blackwell Publishing Inc, 2012
Abstract: Previous picture-word interference (PWI) fMRI-paradigms revealed ambiguous mechanisms underlying facilitation and inhibition in healthy subjects. Lexical distractors revealed increased (enhancement) or decreased (suppression) activation in language and monitoring/control areas. Performing a secondary examination and data analysis, we aimed to illuminate the relation between behavioral and neural interference effects comparing target-related distractors (REL) with unrelated distractors (UNREL). We hypothesized that interference involves both (A) suppression due to priming and (B) enhancement due to simultaneous distractor and target processing. Comparisons to UNREL should remain distractor unspecific even at a low threshold. (C) Distractor types with common characteristics should reveal overlapping brain areas. In a 3T MRI scanner, participants were asked to name pictures while auditory words were presented (stimulus onset asynchrony [SOA] = –200 msec). Associatively and phonologically related distractors speeded responses (facilitation), while categorically related distractors slowed them down (inhibition) compared to UNREL. As a result, (A) reduced brain activations indeed resembled previously reported patterns of neural priming. Each target-related distractor yielded suppressions at least in areas associated with vision and conflict/competition monitoring (anterior cingulate cortex [ACC]), revealing least priming for inhibitors. (B) Enhancements concerned language-related but distractor-unspecific regions. (C) Some wider brain regions were commonly suppressed for combinations of distractor types. Overlapping areas associated with conceptual priming were found for facilitatory distractors (inferior frontal gyri), and areas related to phonetic/articulatory processing (precentral gyri and left parietal operculum/insula) for distractors sharing feature overlap. Each distractor with semantic relatedness revealed nonoverlapping suppressions in lexical-phonological areas (superior temporal regions). To conclude, interference combines suppression of areas well known from neural priming and enhancement of language-related areas caused by dual activation from target and distractor. Differences between interference and priming need to be taken into account. The present interference paradigm has the potential to reveal the functioning of word-processing stages, cognitive control, and responsiveness to priming at the same time.
Keyword: Original Research
URL: https://doi.org/10.1002/brb3.31
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345356
http://www.ncbi.nlm.nih.gov/pubmed/22574280
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20
Enhancement and suppression in a lexical interference fMRI-paradigm: Mechanisms of Lexical Interference
In: Brain and Behavior. - 2, 2 (2012) , 109-127, ISSN: 2162-3279 (2012)
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