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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 12 of 12 1 Common variation near ROBO2 is associated with expressive vocabulary in infancy St Pourcain, Beate; Cents, Rolieke A. M.; Whitehouse, Andrew J. O.. - : Nature Publishing Group, 2014 BASE Show details 2 Genome-Wide Association Study of Receptive Language Ability of 12-Year-Olds Harlaar, Nicole; Meaburn, Emma L.; Hayiou-Thomas, Marianna E.. - : American Speech-Language-Hearing Association, 2014 BASE Show details 3 Genome-wide association study of receptive language ability of 12-year-olds Harlaar, Nicole; Meaburn, Emma L.; Hayiou-Thomas, Marianna E.. - : American Speech, 2014 BASE Show details 4 Common variation near ROBO2 is associated with expressive vocabulary in infancy St Pourcain, Beate; Cents, Rolieke A. M.; Whitehouse, Andrew J. O.; Haworth, Claire M. A.; Davis, Oliver S. P.; O'Reilly, Paul F.; Roulstone, Susan; Wren, Yvonne; Ang, Qi W.; Velders, Fleur P.; Evans, David M.; Kemp, John P.; Warrington, Nicole M.; Miller, Laura; Timpson, Nicholas J.; Ring, Susan M.; Verhulst, Frank C.; Hofman, Albert; Rivadeneira, Fernando; Meaburn, Emma L.; Price, Thomas S.; Dale, Philip S.; Pillas, Demetris; Yliherva, Anneli; Rodriguez, Alina; Golding, Jean; Jaddoe, Vincent W. V.; Jarvelin, Marjo-Riitta; Plomin, Robert; Pennell, Craig E.; Tiemeier, Henning. - : Nature Publishing Group, 2014 Abstract: Twin studies suggest that expressive vocabulary at ~24 months is modestly heritable. However, the genes influencing this early linguistic phenotype are unknown. Here we conduct a genome-wide screen and follow-up study of expressive vocabulary in toddlers of European descent from up to four studies of the EArly Genetics and Lifecourse Epidemiology consortium, analysing an early (15-18 months, 'one-word stage', N=8,889) and a later (24-30 months, 'two-word stage', NTotal=10,819) phase of language acquisition. For the early phase, one single-nucleotide polymorphism (rs7642482) at 3p12.3 near ROBO2, encoding a conserved axon-binding receptor, reaches the genome-wide significance level (P=1.3×10) in the combined sample. This association links language-related common genetic variation in the general population to a potential autism susceptibility locus and a linkage region for dyslexia, speech-sound disorder and reading. The contribution of common genetic influences is, although modest, supported by genome-wide complex trait analysis (meta-GCTA h=0.13, meta-GCTA h =0.14) and in concordance with additional twin analysis (5,733 pairs of European descent, h=0.20). Keyword: 1300 Biochemistry; 1600 Chemistry; 3100 Physics and Astronomy; General Biochemistry; General Chemistry; General Physics and Astronomy; Genetics and Molecular Biology URL: https://espace.library.uq.edu.au/view/UQ:351771 BASE Hide details 5 Genome-wide association study of receptive language ability of 12-year-olds Harlaar, Nicole; Meaburn, Emma L.; Hayiou-Thomas, Marianna E.. - : American Speech - Language - Hearing Association, 2014 BASE Show details 6 Common variation near ROBO2 is associated with expressive vocabulary in infancy St Pourcain, Beate; Cents, Rolieke A. M.; Whitehouse, Andrew J. O.. - : Nature Publishing Group, 2014 BASE Show details 7 Childhood intelligence is heritable, highly polygenic and associated with FNBP1L Benyamin, B.; Pourcain, Bst; Davis, O. S.. - : Nature Publishing Group, 2014 BASE Show details 8 Common DNA Markers Can Account for More Than Half of the Genetic Influence on Cognitive Abilities Plomin, Robert; Haworth, Claire M. A.; Meaburn, Emma L.. - : SAGE Publications, 2013 BASE Show details 9 Genotype by environment interactions in cognitive ability: a survey of 14 studies from four countries covering four age groups Molenaar, Dylan; van der Sluis, Sophie; Boomsma, Dorret I.. - : Springer New York, 2013 BASE Show details 10 Socioeconomic status (SES) and children's intelligence (IQ): In a uk-representative sample SES moderates the environmental, not genetic, effect on IQ Hanscombe, Ken B.; Trzaskowski, Maciej; Haworth, Claire M. A.. - : Public Library of Science (PLoS), 2012 BASE Show details 11 Socioeconomic status (SES) and children's intelligence (IQ) : in a UK-representative sample SES moderates the environmental, not genetic, effect on IQ Hanscombe, Ken B.; Trzaskowski, Maciej; Haworth, Claire M. A.. - : Public Library of Science, 2012 BASE Show details 12 Two by two : a twin study of second-language acquisition Dale, Philip S.; Harlaar, Nicole; Haworth, Claire M. A.. - : Sage Publications Ltd., 2010 BASE Show details

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