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An Interactive Teaching Tool Describing Resistance Evolution and Basic Economics of Insecticide-Based Pest Management.
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In: Insects, vol 13, iss 2 (2022)
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Surnames in south-eastern France: structure of the rural population during the 19th century through isonymy
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In: ISSN: 0021-9320 ; EISSN: 1469-7599 ; Journal of Biosocial Science ; https://hal.archives-ouvertes.fr/hal-03521816 ; Journal of Biosocial Science, Cambridge University Press (CUP), In press, ⟨10.1017/S0021932021000699⟩ (2022)
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TIPD : Taiwan Indigenous Peoples open research Data 台灣原住民基礎開放研究資料庫 ...
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An Interactive Teaching Tool Describing Resistance Evolution and Basic Economics of Insecticide-Based Pest Management
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In: Insects; Volume 13; Issue 2; Pages: 169 (2022)
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Adaptation of the Health Literacy Survey Questionnaire (HLS19-Q) for Russian-Speaking Populations—International Collaboration across Germany, Israel, Kazakhstan, Russia, and the USA
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In: International Journal of Environmental Research and Public Health; Volume 19; Issue 6; Pages: 3572 (2022)
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Agent-Based Modeling of Autosomal Recessive Deafness 1A (DFNB1A) Prevalence with Regard to Intensity of Selection Pressure in Isolated Human Population
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In: Biology; Volume 11; Issue 2; Pages: 257 (2022)
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Abstract:
An increase in the prevalence of autosomal recessive deafness 1A (DFNB1A) in populations of European descent was shown to be promoted by assortative marriages among deaf people. Assortative marriages became possible with the widespread introduction of sign language, resulting in increased genetic fitness of deaf individuals and, thereby, relaxing selection against deafness. However, the effect of this phenomenon was not previously studied in populations with different genetic structures. We developed an agent-based computer model for the analysis of the spread of DFNB1A. Using this model, we tested the impact of different intensities of selection pressure against deafness in an isolated human population over 400 years. Modeling of the “purifying” selection pressure on deafness (“No deaf mating” scenario) resulted in a decrease in the proportion of deaf individuals and the pathogenic allele frequency. Modeling of the “relaxed” selection (“Assortative mating” scenario) resulted in an increase in the proportion of deaf individuals in the first four generations, which then quickly plateaued with a subsequent decline and a decrease in the pathogenic allele frequency. The results of neutral selection pressure modeling (“Random mating” scenario) showed no significant changes in the proportion of deaf individuals or the pathogenic allele frequency after 400 years.
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Keyword:
agent-based computer modeling; assortative mating; genetic fitness; GJB2; hereditary deafness; isolated population; sign language
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URL: https://doi.org/10.3390/biology11020257
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Generating Samples of Diasporic Minority Populations: A Chilean Example
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In: Targeting International Audiences: Current and Future Approaches to International Broadcasting Research ; 3 ; CIBAR Proceedings ; 138-149 ; Conference of International Broadcasters' Audience Research Services (CIBAR) ; XX (2022)
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Attitudes towards the collection and linkage of maltreatment data for research: A qualitative study
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In: Int J Popul Data Sci (2022)
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Brazilian phonoaudiology telepractice before and during the COVID-19 pandemic
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In: Revista CEFAC, Vol 24, Iss 1 (2022) (2022)
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Revisiting the Amdo Sprachbund: Genes, languages, and beyond
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In: Himalayan Linguistics, vol 20, iss 3 (2021)
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Genetic origins, singularity, and heterogeneity of Basques
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In: ISSN: 0960-9822 ; EISSN: 1879-0445 ; Current Biology - CB ; https://hal-pasteur.archives-ouvertes.fr/pasteur-03199264 ; Current Biology - CB, Elsevier, 2021, ⟨10.1016/j.cub.2021.03.010⟩ (2021)
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Функционирование инновационно-консультационной инфраструктуры в АПК ... : The functioning of innovation and consulting infrastructure in the agro-industrial complex ...
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Evidence of the interplay of genetics and culture in Ethiopia. ...
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International Bilingual Journal of Culture, Anthropology and Linguistics ...
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Quelques spécificités du sens de démocratie dans la terminologie juridique ...
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Extreme founder effect associated with oculocutaneous albinism type 1 (OCA1) on the island of Nias/Indonesia:How clinical genetics may help population genetics
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Transformative Transportation Survey Methods: Enhancing Household Transportation Survey Methods for Hard-To-Reach Populations
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In: Sociology Faculty Publications and Presentations (2021)
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Quantifying Holistic Capacity Response and Healthcare Resilience in Tackling COVID-19: Assessment of Country Capacity by MCDM ...
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Quantifying Holistic Capacity Response and Healthcare Resilience in Tackling COVID-19: Assessment of Country Capacity by MCDM ...
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Quantifying Holistic Capacity Response and Healthcare Resilience in Tackling COVID-19: Assessment of Country Capacity by MCDM.xlsx ...
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