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1
Stimulating Multiple-Demand Cortex Enhances Vocabulary Learning
Sliwinska, Magdalena W.; Violante, Inês R.; Wise, Richard J.S.. - : Society for Neuroscience, 2017
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Stimulating Multiple-Demand Cortex Enhances Vocabulary Learning
Abstract: It is well established that networks within multiple-demand cortex (MDC) become active when diverse skills and behaviors are being learnt. However, their causal role in learning remains to be established. In the present study, we first performed functional magnetic resonance imaging on healthy female and male human participants to confirm that MDC was most active in the initial stages of learning a novel vocabulary, consisting of pronounceable nonwords (pseudowords), each associated with a picture of a real object. We then examined, in healthy female and male human participants, whether repetitive transcranial magnetic stimulation of a frontal midline node of the cingulo-opercular MDC affected learning rates specifically during the initial stages of learning. We report that stimulation of this node, but not a control brain region, substantially improved both accuracy and response times during the earliest stage of learning pseudoword–object associations. This stimulation had no effect on the processing of established vocabulary, tested by the accuracy and response times when participants decided whether a real word was accurately paired with a picture of an object. These results provide evidence that noninvasive stimulation to MDC nodes can enhance learning rates, thereby demonstrating their causal role in the learning process. We propose that this causal role makes MDC candidate target for experimental therapeutics; for example, in stroke patients with aphasia attempting to reacquire a vocabulary.
URL: http://epubs.surrey.ac.uk/846184/1/Stimulating%20Multiple-Demand%20Cortex%20Enhances%20Vocabulary%20Learning.pdf
https://doi.org/10.1523/JNEUROSCI.3857-16.2017
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3
Network dysfunction predicts speech production after left hemisphere stroke
Geranmayeh, Fatemeh; Leech, Robert; Wise, Richard J.S.. - : Lippincott Williams & Wilkins, 2016
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4
Semantic retrieval during overt picture description: Left anterior temporal or the parietal lobe?
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5
Overlapping Networks Engaged during Spoken Language Production and Its Cognitive Control
Geranmayeh, Fatemeh; Wise, Richard J.S.; Mehta, Amrish. - : Society for Neuroscience, 2014
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6
Sensory-Motor Integration during Speech Production Localizes to Both Left and Right Plana Temporale
Simmonds, Anna J.; Leech, Robert; Collins, Catherine. - : Society for Neuroscience, 2014
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7
The neurobiology of language: Two years later
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 116 (2011) 3, 103-104
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8
The effect of delayed auditory feedback on activity in the temporal lobe while speaking: a positron emission tomography study
In: Journal of speech, language, and hearing research. - Rockville, Md. : American Speech-Language-Hearing Association 53 (2010) 2, 226-236
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9
The neural processing of masked speech: evidence for different mechanisms in the left and right temporal lobes
Wise, Richard J.S.; Rosen, Stuart; Scott, Sophie K.. - : Acoustical Society of America, 2009
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10
Patients with hemianopic alexia adopt an inefficient eye movement strategy when reading text
In: Brain. - Oxford : Oxford Univ. Press 129 (2006) 1, 158-167
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11
Lexical retrieval constrained by sound structure: The role of the left inferior frontal gyrus
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 92 (2005) 3, 309-319
OLC Linguistik
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12
Lexical retrieval constrained by sound structure : the role of the left inferior frontal gyrus
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 92 (2005) 3, 309-319
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13
The functional neuroanatomy of prelexical processing in speech perception
In: Cognition. - Amsterdam [u.a] : Elsevier 92 (2004) 1-2, 13-46
OLC Linguistik
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14
The functional neuroanatomy of prelexical processing in speech perception
In: Cognition. - Amsterdam [u.a] : Elsevier 92 (2004) 1-2, 13-45
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15
Monitoring and the Controlled Processing of Meaning: Distinct Prefrontal Systems
Sharp, David J.; Scott, Sophie K.; Wise, Richard J.S.. - : Oxford University Press, 2004
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16
PET and fMRI studies of the neural basis of speech perception
In: Speech communication. - Amsterdam [u.a.] : Elsevier 41 (2003) 1, 23-34
OLC Linguistik
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17
Functional imaging and language: A critical guide to methodology and analysis
In: Speech communication. - Amsterdam [u.a.] : Elsevier 41 (2003) 1, 7-22
OLC Linguistik
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18
The nature of speech perception : the psychophysics of speech perception III
Schouten, M. E. H. (Hrsg.); Scott, Sophie K. (Mitarb.); Wise, Richard J.S. (Mitarb.)...
In: Speech communication. - Amsterdam [u.a.] : Elsevier 41 (2003) 1, 1-270
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19
Temporal lobe regions engaged during normal speech comprehension
In: Brain. - Oxford : Oxford Univ. Press 126 (2003) 5, 1193-1201
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20
Speech production : Wernicke, Broca and beyond
In: Brain. - Oxford : Oxford Univ. Press 125 (2002) 8, 1829-1838
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