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Investigating the effects of handedness on the consistency of lateralization for speech production and semantic processing tasks using functional transcranial Doppler sonography
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Testing the unitary theory of language lateralization using functional transcranial Doppler sonography in adults
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CATALISE : a multinational and multidisciplinary Delphi consensus study. Identifying language impairments in children
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CATALISE : a multinational and multidisciplinary Delphi consensus study. Identifying language impairments in children
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Increased prevalence of sex chromosome aneuploidies in specific language impairment and dyslexia
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CNTNAP2 variants affect early language development in the general population
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Overlaps between autism and language impairment: phenomimicry or shared etiology?
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Lower-frequency event-related desynchronization: a signature of late mismatch responses to sounds, which is reduced or absent in children with specific language impairment
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Genes, cognition, and communication: insights from neurodevelopmental disorders
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Weak hand preference in children with down syndrome is associated with language deficits
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Weak hand preference in children with Down syndrome is associated with language deficits
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Heritability of specific language impairment depends on diagnostic criteria
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Abstract:
Heritability estimates for specific language impairment (SLI) have been inconsistent. Four twin studies reported heritability of 0.5 or more, but a recent report from the Twins Early Development Study found negligible genetic influence in 4-year-olds. We considered whether the method of ascertainment influenced results and found substantially higher heritability if SLI was defined in terms of referral to speech and language pathology services than if defined by language test scores. Further analysis showed that presence of speech difficulties played a major role in determining whether a child had contact with services. Childhood language disorders that are identified by population screening are likely to have a different phenotype and different etiology from clinically referred cases. Genetic studies are more likely to find high heritability if they focus on cases who have speech difficulties and who have been referred for intervention.
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Keyword:
Original Articles
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URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2324210 http://www.ncbi.nlm.nih.gov/pubmed/17919296 https://doi.org/10.1111/j.1601-183X.2007.00360.x
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Heritable risk factors associated with language impairments
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Is poor frequency modulation detection linked to literacy problems? A comparison of specific reading disability and mild to moderate sensorineural hearing loss
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Speech and non-speech processing in people with specific language impairment: a behavioural and electrophysiological study
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Frequency discrimination deficits in people with specific language impairment : reliability, validity, and linguistic correlates
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