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Alterations to dual stream connectivity predicts response to aphasia therapy following stroke
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Cross-modal emotion recognition and autism-like traits in typically developing children
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An automated approach to examining pausing in the speech of people with dementia
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The influence of contextual constraint on verbal selection mechanisms and its neural correlates in Parkinson’s disease
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Alterations to dual stream connectivity predicts response to aphasia therapy following stroke
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The Suppression of Irrelevant Semantic Representations in Parkinson’s Disease
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Functional correlates of strategy formation and verbal suppression in Parkinson's disease
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Semantic processing in children with cochlear implants: evidence from event-related potentials
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Conversational trouble and repair in dementia: revision of an existing coding framework
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The suppression of irrelevant semantic representations in Parkinson's Disease
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Reading development in children with cochlear implants who communicate via spoken language: A psycholinguistic investigation
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Spelling in children with cochlear implants: evidence of underlying processing differences
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Lexical ambiguity resolution during sentence processing in Parkinson’s disease: An event-related potential study
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Abstract:
Event-related potentials (ERPs) were recorded to investigate lexical ambiguity resolution during sentence processing in 16 people with Parkinson’s disease (PD) and 16 healthy controls. Sentences were presented word-by-word on computer screen, and participants were required to decide if a subsequent target word was related to the meaning of the sentence. The task consisted of related, unrelated and ambiguous trials. For the ambiguous trials, the sentence ended with an ambiguous word and the target was related to one of the meanings of that word, but not the one captured by the sentence context (e.g., ‘He dug with the spade’, Target ‘ACE’). Both groups demonstrated slower reaction times and lower accuracy for the ambiguous condition relative to the unrelated condition, however accuracy was impacted by the ambiguous condition to a larger extent in the PD group. These results suggested that PD patients experience increased difficulties with contextual ambiguity resolution. The ERP results did not reflect increased ambiguity resolution difficulties in PD, as a similar N400 effect was evident for the unrelated and ambiguous condition in both groups. However, the magnitude of the N400 for these conditions was correlated with a measure of inhibition in the PD group, but not the control group. The ERP results suggest that semantic processing may be more compromised in PD patients with increased response inhibition deficits.
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Keyword:
Research Article
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URL: https://doi.org/10.1371/journal.pone.0176281 http://www.ncbi.nlm.nih.gov/pubmed/28475582 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419504/
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Semantic Feature Disturbance in Alzheimer Disease: Evidence from an Object Decision Task
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