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Alterations to dual stream connectivity predicts response to aphasia therapy following stroke
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Cross-modal emotion recognition and autism-like traits in typically developing children
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An automated approach to examining pausing in the speech of people with dementia
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The influence of contextual constraint on verbal selection mechanisms and its neural correlates in Parkinson’s disease
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Alterations to dual stream connectivity predicts response to aphasia therapy following stroke
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The Suppression of Irrelevant Semantic Representations in Parkinson’s Disease
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Functional correlates of strategy formation and verbal suppression in Parkinson's disease
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Semantic processing in children with cochlear implants: evidence from event-related potentials
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Conversational trouble and repair in dementia: revision of an existing coding framework
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The suppression of irrelevant semantic representations in Parkinson's Disease
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Reading development in children with cochlear implants who communicate via spoken language: A psycholinguistic investigation
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Spelling in children with cochlear implants: evidence of underlying processing differences
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N400 and Emotional Word Processing in Parkinson's Disease
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Dissanayaka, Nadeeka N. W.; Au, Tiffany R.; Angwin, Anthony J.; O'Sullivan, John D.; Byrne, Gerard J.; Silburn, Peter A.; Marsh, Rodney; Mellick, George; Copland, David A.. - : John Wiley & Sons, 2017
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Abstract:
Objective: Emotional and cognitive disturbances are common complications in Parkinson’s disease (PD). N400 is an event related potential (ERP) strongly linked to lexical-semantic processing and has demonstrated alterations in amplitude and latency when PD patients performed semantic priming tasks. The present study investigated the role of N400 in an automatic affective priming paradigm in PD. Other ERP components relevant to emotion processing were also examined. Method: Twenty-two PD patients and 17 healthy adults performed an automatic affective priming task while ERPs were recorded using 128 channels. Prime–target word pairs of negative or neutral valence were presented at a stimulus onset asynchrony of 250 ms. Participants were asked to evaluate the valence of the target word by button press. Results: A larger N400 amplitude for incongruent compared with congruent neutral targets was observed at right central and parietal regions and did not differ between PD and controls. PD and controls also displayed larger P300 and late positive potential (LPP) amplitudes for negative compared with neutral targets at central parietal and right frontal regions. In contrast, whereas controls showed a larger slow negative wave (SNW) for negative targets compared with neutral targets at left frontal and left central regions, PD group demonstrated a significant reduction in SNW amplitude difference at the left central region. Conclusion: N400 is intact in PD when processing evaluative judgments of emotional words. P300 and LPP were also intact in PD. The altered left central SNW in PD suggests an ERP marker for emotional dysfunction in PD. (PsycINFO Database Record (c) 2017 APA, all rights reserved) ; No Full Text
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Keyword:
Neurosciences not elsewhere classified
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URL: https://doi.org/10.1037/neu0000333 http://hdl.handle.net/10072/368351
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Lexical ambiguity resolution during sentence processing in Parkinson’s disease: An event-related potential study
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Semantic Feature Disturbance in Alzheimer Disease: Evidence from an Object Decision Task
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