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Source or target first? Comparison of two post-editing strategies with translation students
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In: https://hal.archives-ouvertes.fr/hal-03546151 ; 2022 (2022)
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| 2 |
Trans-Translation Is an Appealing Target for the Development of New Antimicrobial Compounds
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In: EISSN: 2076-2607 ; Microorganisms ; https://hal.archives-ouvertes.fr/hal-03575603 ; Microorganisms, 2022, 10 (1), ⟨10.3390/microorganisms10010003⟩ (2022)
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Abstract:
International audience ; Because of the ever-increasing multidrug resistance in microorganisms, it is crucial that we find and develop new antibiotics, especially molecules with different targets and mechanisms of action than those of the antibiotics in use today. Translation is a fundamental process that uses a large portion of the cell's energy, and the ribosome is already the target of more than half of the antibiotics in clinical use. However, this process is highly regulated, and its quality control machinery is actively studied as a possible target for new inhibitors. In bacteria, ribosomal stalling is a frequent event that jeopardizes bacterial wellness, and the most severe form occurs when ribosomes stall at the 3 '-end of mRNA molecules devoid of a stop codon. Trans-translation is the principal and most sophisticated quality control mechanism for solving this problem, which would otherwise result in inefficient or even toxic protein synthesis. It is based on the complex made by tmRNA and SmpB, and because trans-translation is absent in eukaryotes, but necessary for bacterial fitness or survival, it is an exciting and realistic target for new antibiotics. Here, we describe the current and future prospects for developing what we hope will be a novel generation of trans-translation inhibitors.
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Keyword:
[SDV]Life Sciences [q-bio]; antibiotics; ribosome; SmpB; tmRNA; trans-translation
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URL: https://hal.archives-ouvertes.fr/hal-03575603
https://doi.org/10.3390/microorganisms10010003
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| 3 |
Automatic Normalisation of Early Modern French
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In: https://hal.inria.fr/hal-03540226 ; 2022 (2022)
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| 4 |
Offline Corpus Augmentation for English-Amharic Machine Translation
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In: 2022 The 5th International Conference on Information and Computer Technologies ; https://hal.archives-ouvertes.fr/hal-03547539 ; 2022 The 5th International Conference on Information and Computer Technologies, Mar 2022, New York, United States (2022)
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| 5 |
Non-sexist Language in Vacancy Titles: A Proposal for Drafting and Translation in International Organisations
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In: Journal of International Women's Studies (2022)
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| 6 |
Combating the Misrepresentation of Women in Quran Translations: Translational Interventions
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In: Journal of International Women's Studies (2022)
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Towards an empirical evaluation of translated texts and translation quality ; Vers une évaluation empirique des textes traduits et de la qualité en traduction
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In: https://hal.archives-ouvertes.fr/hal-03584752 ; 2022 (2022)
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| 8 |
DeepL et Google Translate face à l'ambiguïté phraséologique
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In: https://hal.archives-ouvertes.fr/hal-03583995 ; 2022 (2022)
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| 9 |
Language Teaching in Higher Education within a Plurilingual Perspective
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In: L2 Journal, vol 14, iss 2 (2022)
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| 10 |
The Future of Translation in Higher Education: Introduction to the Special Issue
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In: L2 Journal, vol 14, iss 2 (2022)
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| 11 |
Tandem and Translation: A bilingual telecollaboration course in social science translation
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In: L2 Journal, vol 14, iss 2 (2022)
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| 12 |
From Disrupted Classrooms to Human-Machine Collaboration? The Pocket Calculator, Google Translate, and the Future of Language Education
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In: L2 Journal, vol 14, iss 1 (2022)
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| 13 |
Thirty Years of Machine Translation in Language Teaching and Learning: A Review of the Literature
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In: L2 Journal, vol 14, iss 1 (2022)
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| 14 |
A “Hands-On” Approach to Raise Awareness of Technologies: A Pilot Class and its Lessons
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In: L2 Journal, vol 14, iss 1 (2022)
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| 15 |
Do You Speak Translate?: Reflections on the Nature and Role of Translation
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In: L2 Journal, vol 14, iss 1 (2022)
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| 16 |
Current Practices in Translation and L2 Learning in Higher Education: Lessons Learned
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In: L2 Journal, vol 14, iss 2 (2022)
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| 17 |
Exploring Foreign Language Students’ Perceptions of the Guided Use of Machine Translation (GUMT) Model for Korean Writing
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In: L2 Journal, vol 14, iss 1 (2022)
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| 18 |
Machine Translation: Friend or Foe in the Language Classroom?
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In: L2 Journal, vol 14, iss 1 (2022)
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| 19 |
Proficiency and the Use of Machine Translation: A Case Study of Four Japanese Learners
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In: L2 Journal, vol 14, iss 1 (2022)
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| 20 |
Translation Pedagogy in the Comparative Literature Classroom: Close Reading and the Hermeneutic Model of Translation
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In: L2 Journal, vol 14, iss 2 (2022)
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