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Development of a standard of care for patients with valosin-containing protein associated multisystem proteinopathy.
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In: Orphanet journal of rare diseases, vol 17, iss 1 (2022)
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| 2 |
Cortical microstructure in primary progressive aphasia: a multicenter study.
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In: Alzheimer's research & therapy, vol 14, iss 1 (2022)
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Barriers and Facilitators to the Implementation of a Community Doula Program for Black and Pacific Islander Pregnant People in San Francisco: Findings from a Partnered Process Evaluation.
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In: Maternal and child health journal, vol 26, iss 4 (2022)
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Addressing racial/ethnic inequities in vaccine hesitancy and uptake: lessons learned from the California alliance against COVID-19.
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Analysis of ancestry heterozygosity suggests that hybrid incompatibilities in threespine stickleback are environment dependent.
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Thompson, Ken A; Peichel, Catherine L; Rennison, Diana J; McGee, Matthew D; Albert, Arianne YK; Vines, Timothy H; Greenwood, Anna K; Wark, Abigail R; Brandvain, Yaniv; Schumer, Molly; Schluter, Dolph
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In: PLoS biology, vol 20, iss 1 (2022)
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Abstract:
Hybrid incompatibilities occur when interactions between opposite ancestry alleles at different loci reduce the fitness of hybrids. Most work on incompatibilities has focused on those that are "intrinsic," meaning they affect viability and sterility in the laboratory. Theory predicts that ecological selection can also underlie hybrid incompatibilities, but tests of this hypothesis using sequence data are scarce. In this article, we compiled genetic data for F2 hybrid crosses between divergent populations of threespine stickleback fish (Gasterosteus aculeatus L.) that were born and raised in either the field (seminatural experimental ponds) or the laboratory (aquaria). Because selection against incompatibilities results in elevated ancestry heterozygosity, we tested the prediction that ancestry heterozygosity will be higher in pond-raised fish compared to those raised in aquaria. We found that ancestry heterozygosity was elevated by approximately 3% in crosses raised in ponds compared to those raised in aquaria. Additional analyses support a phenotypic basis for incompatibility and suggest that environment-specific single-locus heterozygote advantage is not the cause of selection on ancestry heterozygosity. Our study provides evidence that, in stickleback, a coarse-albeit indirect-signal of environment-dependent hybrid incompatibility is reliably detectable and suggests that extrinsic incompatibilities can evolve before intrinsic incompatibilities.
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Keyword:
Agricultural and Veterinary Sciences; Biological Sciences; Developmental Biology; Genetics; Medical and Health Sciences
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URL: https://escholarship.org/uc/item/3f26386d
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| 7 |
Protocol for the development of the international population registry for aphasia after stroke (I-PRAISE)
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In: Research outputs 2014 to 2021 (2022)
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An aphasia research agenda – a consensus statement from the collaboration of aphasia trialists
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In: Research outputs 2014 to 2021 (2022)
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| 9 |
The Terms of “You(s)”: How the Term of Address Used by Conversational Agents Influences User Evaluations in French and German Linguaculture ...
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| 11 |
The 'real-life' benefit of hearing preservation cochlear implantation in the paediatric population ...
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| 12 |
R-Loops und replikativer Stress als Angriffspunkt für eine zielgerichtete Therapie beim Myelodysplastischen Syndrom
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Brazilian phonoaudiology telepractice before and during the COVID-19 pandemic
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In: Revista CEFAC, Vol 24, Iss 1 (2022) (2022)
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| 14 |
Perception of medical education by learners and teachers during the COVID-19 pandemic: a cross-sectional survey of online teaching
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In: ISSN: 1087-2981 ; Medical Education Online ; https://hal.inrae.fr/hal-03329784 ; Medical Education Online, Co-Action Publishing, 2021, 26 (1), pp.1919042. ⟨10.1080/10872981.2021.1919042⟩ (2021)
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| 15 |
Medical students attitudes toward and intention to work with the underserved: a systematic review and meta-analysis
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In: ISSN: 1472-6920 ; BMC Medical Education ; https://www.hal.inserm.fr/inserm-03313263 ; BMC Medical Education, BioMed Central, 2021, 21 (1), pp.129. ⟨10.1186/s12909-021-02517-x⟩ (2021)
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| 16 |
Reliability of perceptual measurement of Apraxia of Speech characteristics
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| 17 |
Disambiguation of Medical Abbreviations in French with Supervised Methods
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In: Studies in Health Technology and Informatics ; https://hal.archives-ouvertes.fr/hal-03335532 ; Studies in Health Technology and Informatics, 2021, ⟨10.3233/shti210171⟩ (2021)
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| 18 |
Social Support Networks within Transgender Facebook Groups: Facing a “Therapeutic Shield” in France
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In: Advances in Trans Studies: Moving Toward Gender Expansion and Trans Hope ; https://hal.archives-ouvertes.fr/hal-03417780 ; Advances in Trans Studies: Moving Toward Gender Expansion and Trans Hope, Emerald Publishing Limited, pp.207-222, 2021, Advances in Gender Research, 978-1-80262-030-6. ⟨10.1108/S1529-212620210000032014⟩ (2021)
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| 19 |
Tau PET imaging with 18F-PI-2620 in aging and neurodegenerative diseases.
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In: European journal of nuclear medicine and molecular imaging, vol 48, iss 7 (2021)
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| 20 |
Bilingual advantages in executive functioning: Evidence from a low-income sample
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In: FIRST LANGUAGE, vol 41, iss 6 (2021)
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