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Constraint and multimodal approaches to therapy for chronic aphasia: A systematic review and meta-analysis ...
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Constraint-induced or multi-modal personalized aphasia rehabilitation (COMPARE): A randomized controlled trial for stroke-related chronic aphasia
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In: Research outputs 2014 to 2021 (2019)
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Fidelity protocol for the Action Success Knowledge (ASK) trial: a psychosocial intervention administered by speech and language therapists to prevent depression in people with post-stroke aphasia
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Experiences of people with severe aphasia and spouses attending an Interdisciplinary Community Aphasia Group ...
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Experiences of people with severe aphasia and spouses attending an Interdisciplinary Community Aphasia Group ...
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Discourse recovery after severe traumatic brain injury: exploring the first year
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In: Brain Inj (2019)
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Content Analysis of Tweets by People with Traumatic Brain Injury (TBI): Implications for Rehabilitation and Social Media Goals
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Fidelity protocol for the Action Success Knowledge (ASK) trial: a psychosocial intervention administered by speech and language therapists to prevent depression in people with post-stroke aphasia
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Discourse recovery after severe traumatic brain injury : exploring the first year
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Constraint-induced or multi-modal personalized aphasia rehabilitation (COMPARE): a randomized controlled trial for stroke-related chronic aphasia
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Rose, Miranda L.; Copland, David; Nickels, Lyndsey; Togher, Leanne; Meinzer, Marcus; Rai, Tapan; Cadilhac, Dominique A.; Kim, Joosup; Foster, Abby; Carragher, Marcella; Hurley, Melanie; Godecke, Erin. - : Sage Publications, 2019
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Abstract:
Rationale: The comparative efficacy and cost-effectiveness of constraint-induced and multi-modality aphasia therapy in chronic stroke are unknown. Aims and hypotheses: In the COMPARE trial, we aim to determine whether Multi-Modal Aphasia Treatment (M-MAT) and Constraint-Induced Aphasia Therapy Plus (CIAT-Plus) are superior to usual care (UC) for chronic post-stroke aphasia. Primary hypothesis: CIAT-Plus and M-MAT will reduce aphasia severity (Western Aphasia Battery-Revised Aphasia Quotient (WAB-R-AQ)) compared with UC: CIAT-Plus superior for moderate aphasia; M-MAT superior for mild and severe aphasia. Sample size estimates:A total of 216 participants (72 per arm) will provide 90% power to detect a 5-point difference on the WAB-R-AQ between CIAT-Plus or M-MAT and UC at alpha = 0.05. Methods and design: Prospective, randomized, parallel group, open-label, assessor blinded trial. Participants: Stroke >6 months; aphasia severity categorized using WAB-R-AQ. Computer-generated blocked and stratified randomization by aphasia severity (mild, moderate, and severe), to 3 arms: CIAT-Plus, M-MAT (both 30 h therapy over two weeks); UC (self-reported usual community care). Study outcomes: WAB-R-AQ immediately post-intervention. Secondary outcomes: WAB-R-AQ at 12-week follow-up; naming scores, discourse measures, Communicative Effectiveness Index, Scenario Test, and Stroke and Aphasia Quality of Life Scale-39 g immediately and at 12 weeks post-intervention; incremental cost-effectiveness ratios compared with UC at 12 weeks. Discussion: This trial will determine whether CIAT-Plus and M-MAT are superior and more cost-effective than UC in chronic aphasia. Participant subgroups with the greatest response to CIAT-Plus and M-MAT will be described.
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Keyword:
2808 Neurology; Aphasia therapy; Constraint; Intensity; Multimodal; Randomized controlled trial; Rehabilitation; Stroke
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URL: https://espace.library.uq.edu.au/view/UQ:5d73ed9
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A how-to guide to aphasia services: celebrating Professor Linda Worrall’s contribution to the field
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Fidelity protocol for the Action Success Knowledge (ASK) trial: a psychosocial intervention administered by speech and language therapists to prevent depression in people with post-stroke aphasia
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Tidier descriptions of speech and language therapy interventions for people with aphasia; consensus from the release collaboration
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In: Research outputs 2014 to 2021 (2018)
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Procedural discourse performance in adults with severe traumatic brain injury at 3 and 6 months post injury
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In: Brain Inj (2018)
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Procedural discourse performance in adults with severe traumatic brain injury at 3 and 6 months post injury
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Cognitive-communication and psychosocial functioning 12 months after severe traumatic brain injury
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Strengthening the quality of longitudinal research into cognitive-communication recovery after traumatic brain injury : a systematic review
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Language and cognitive communication disorder during post-traumatic amnesia: profiles of recovery after TBI from three cases
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Social communication during post-traumatic amnesia and the post-acute period after traumatic brain injury
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Treatment for people with chronic aphasia - investigation of high and low intensity, constraint and multimodal treatments
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