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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 Hits 1 – 20 of 27 1 Methods for fMRI analysis White, Corey N.; Poldrack, Russell A. In: Methodology (Hoboken, NJ, 2018), p. 565-596 MPI für Psycholinguistik Show details 2 Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. Savage, Jeanne E; Jansen, Philip R; Stringer, Sven; Watanabe, Kyoko; Bryois, Julien; de Leeuw, Christiaan A; Nagel, Mats; Awasthi, Swapnil; Barr, Peter B; Coleman, Jonathan RI; Grasby, Katrina L; Hammerschlag, Anke R; Kaminski, Jakob A; Karlsson, Robert; Krapohl, Eva; Lam, Max; Nygaard, Marianne; Reynolds, Chandra A; Trampush, Joey W; Young, Hannah; Zabaneh, Delilah; Hägg, Sara; Hansell, Narelle K; Karlsson, Ida K; Linnarsson, Sten; Montgomery, Grant W; Muñoz-Manchado, Ana B; Quinlan, Erin B; Schumann, Gunter; Skene, Nathan G; Webb, Bradley T; White, Tonya; Arking, Dan E; Avramopoulos, Dimitrios; Bilder, Robert M; Bitsios, Panos; Burdick, Katherine E; Cannon, Tyrone D; Chiba-Falek, Ornit; Christoforou, Andrea; Cirulli, Elizabeth T; Congdon, Eliza; Corvin, Aiden; Davies, Gail; Deary, Ian J; DeRosse, Pamela; Dickinson, Dwight; Djurovic, Srdjan; Donohoe, Gary; Conley, Emily Drabant; Eriksson, Johan G; Espeseth, Thomas; Freimer, Nelson A; Giakoumaki, Stella; Giegling, Ina; Gill, Michael; Glahn, David C; Hariri, Ahmad R; Hatzimanolis, Alex; Keller, Matthew C; Knowles, Emma; Koltai, Deborah; Konte, Bettina; Lahti, Jari; Le Hellard, Stephanie; Lencz, Todd; Liewald, David C; London, Edythe; Lundervold, Astri J; Malhotra, Anil K; Melle, Ingrid; Morris, Derek; Need, Anna C; Ollier, William; Palotie, Aarno; Payton, Antony; Pendleton, Neil; Poldrack, Russell A; Räikkönen, Katri; Reinvang, Ivar; Roussos, Panos; Rujescu, Dan; Sabb, Fred W; Scult, Matthew A; Smeland, Olav B; Smyrnis, Nikolaos; Starr, John M; Steen, Vidar M; Stefanis, Nikos C; Straub, Richard E; Sundet, Kjetil; Tiemeier, Henning; Voineskos, Aristotle N; Weinberger, Daniel R; Widen, Elisabeth; Yu, Jin; Abecasis, Goncalo; Andreassen, Ole A; Breen, Gerome; Christiansen, Lene In: Nature genetics, vol 50, iss 7 (2018) Abstract: Intelligence is highly heritable1 and a major determinant of human health and well-being2. Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in intelligence3-7, but much about its genetic underpinnings remains to be discovered. Here, we present a large-scale genetic association study of intelligence (n = 269,867), identifying 205 associated genomic loci (190 new) and 1,016 genes (939 new) via positional mapping, expression quantitative trait locus (eQTL) mapping, chromatin interaction mapping, and gene-based association analysis. We find enrichment of genetic effects in conserved and coding regions and associations with 146 nonsynonymous exonic variants. Associated genes are strongly expressed in the brain, specifically in striatal medium spiny neurons and hippocampal pyramidal neurons. Gene set analyses implicate pathways related to nervous system development and synaptic structure. We confirm previous strong genetic correlations with multiple health-related outcomes, and Mendelian randomization analysis results suggest protective effects of intelligence for Alzheimer's disease and ADHD and bidirectional causation with pleiotropic effects for schizophrenia. These results are a major step forward in understanding the neurobiology of cognitive function as well as genetically related neurological and psychiatric disorders. Keyword: Adolescent; Biological Sciences; Brain; Developmental Biology; Female; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Intelligence; Male; Medical and Health Sciences; Middle Aged; Polymorphism; Quantitative Trait Loci; Single Nucleotide URL: https://escholarship.org/uc/item/869275xx BASE Hide details 3 Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018). Lam, Max; Trampush, Joey W; Yu, Jin... In: Twin research and human genetics : the official journal of the International Society for Twin Studies, vol 21, iss 5 (2018) BASE Show details 4 Beyond dopamine: The noradrenergic system and mental effort Malecek, Nicholas J.; Poldrack, Russell A.; Kurzban, Robert In: Behavioral and brain sciences. - New York, NY [u.a.] : Cambridge Univ. Press 36 (2013) 6, 698-699 OLC Linguistik Show details 5 Handbook of functional MRI data analysis Poldrack, Russell A.; Mumford, Jeanette A.; Nichols, Thomas. - Cambridge : Cambridge University Press, 2011 MPI für Psycholinguistik Show details 6 Towards an ontology of cognitive control Lenartowicz, Agatha; Kalar, Donald J.; Congdon, Eliza... In: Topics in cognitive science. - Hoboken, NJ [u.a.] : Wiley 2 (2010) 4, 678-692 BLLDB Show details 7 Decoding the Large-Scale Structure of Brain Function by Classifying Mental States Across Individuals Poldrack, Russell A.; Halchenko, Yaroslav; Hanson, Stephen José. - 2009 BASE Show details 8 Secondary-task effects on classification learning Foerde, Karin; Poldrack, Russell A; Knowlton, Barbara J In: Memory & cognition. - Heidelberg [u.a.] : Springer 35 (2007) 5, 864 OLC Linguistik Show details 9 The neural substrates of visual perceptual learning of words: implications for the visual word form area hypothesis Poldrack, Russell A.; Xue, Gui In: Journal of cognitive neuroscience. - Cambridge, Mass. : MIT Press Journals 19 (2007) 10, 1643-1655 BLLDB OLC Linguistik Show details 10 Secondary-task effects on classification learning Foerde, Karin; Poldrack, Russell A.; Knowlton, Barbara J. In: Memory & cognition. - Heidelberg [u.a.] : Springer 35 (2007) 5, 864-874 OLC Linguistik Show details 11 Functional neuroimaging of skill learning Poldrack, Russell A.; Willingham, Daniel T. In: Handbook of functional neuroimaging of cognition (Cambridge, Mass. s, 2006), p. 113-148 MPI für Psycholinguistik Show details 12 Functional neuroimaging of skill learning Poldrack, Russell A.; Willingham, Daniel T. In: Handbook of functional neuroimaging of cognition (Cambridge, Mass. s, 2006), p. 113-148 MPI für Psycholinguistik Show details 13 The cognitive neuroscience of reading Poldrack, Russell A. (Herausgeber); Sandak, Rebecca (Herausgeber). - [London] : Routledge, 2004 BLLDB UB Frankfurt Linguistik Show details 14 Neural deficits in children with dyslexia ameliorated by behavioral remediation: Evidence from functional MRI Temple, Elise; Deutsch, Gayle K.; Poldrack, Russell A.. - : The National Academy of Sciences, 2003 BASE Show details 15 Relations between the neural bases of dynamic auditory processing and phonological processing : evidence from fMRI Poldrack, Russell A.; Temple, Elise; Protopapas, Athanassios... In: Journal of cognitive neuroscience. - Cambridge, Mass. : MIT Press Journals 13 (2001) 5, 687-697 BLLDB Show details 16 Relations Between the Neural Bases of Dynamic Auditory Processing and Phonological Processing: Evidence from fMRI Poldrack, Russell A.; Temple, Elise; Protopapas, Athanassios... In: Journal of cognitive neuroscience. - Cambridge, Mass. : MIT Press Journals 13 (2001) 5, 687-697 OLC Linguistik Show details 17 Characterizing the neural mechanisms of skill learning and repetition priming : evidence from mirror reading Poldrack, Russell A.; Gabrieli, John D. E. In: Brain. - Oxford : Oxford Univ. Press 124 (2001) 1, 67-82 BLLDB Show details 18 Interactive memory systems in the human brain Poldrack, Russell A.; Clark, J.; Paré-Blagoev, Juliana... In: Nature. - London : Macmillan Publishers Limited, part of Springer Nature 414 (2001) 6863, 546-550 BLLDB Show details 19 Convergent cortical representation of semantic processing in billinguals Illes, Judy; Francis, Wendy S.; Desmond, John E.... In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 70 (1999) 3, 347-363 BLLDB Show details 20 Functional neuroimaging of word processing in normal and dyslexic readers Demb, Jonathan B.; Poldrack, Russell A.; Gabrieli, John D.E. In: Converging methods for understanding reading and dyslexia (Cambridge, Mass, 1999), p. 243-304 MPI für Psycholinguistik Show details Page: 1 2

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