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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 4 5...12 Hits 1 – 20 of 227 1 Family history of FXTAS is associated with age-related cognitive-linguistic decline among mothers with the FMR1 premutation. Klusek, Jessica; Fairchild, Amanda; Moser, Carly... In: Journal of neurodevelopmental disorders, vol 14, iss 1 (2022) BASE Show details 2 Cortical microstructure in primary progressive aphasia: a multicenter study. Illán-Gala, Ignacio; Montal, Victor; Borrego-Écija, Sergi; Mandelli, Maria Luisa; Falgàs, Neus; Welch, Ariane E; Pegueroles, Jordi; Santos-Santos, Miguel; Bejanin, Alexandre; Alcolea, Daniel; Dols-Icardo, Oriol; Belbin, Olivia; Sánchez-Saudinós, Mª Belén; Bargalló, Nuria; González-Ortiz, Sofía; Lladó, Albert; Blesa, Rafael; Dickerson, Bradford C; Rosen, Howard J; Miller, Bruce L; Lleó, Alberto; Gorno-Tempini, Maria Luisa; Sánchez-Valle, Raquel; Fortea, Juan In: Alzheimer's research & therapy, vol 14, iss 1 (2022) Abstract: BackgroundCortical mean diffusivity is a novel imaging metric sensitive to early changes in neurodegenerative syndromes. Higher cortical mean diffusivity values reflect microstructural disorganization and have been proposed as a sensitive biomarker that might antedate macroscopic cortical changes. We aimed to test the hypothesis that cortical mean diffusivity is more sensitive than cortical thickness to detect cortical changes in primary progressive aphasia (PPA).MethodsIn this multicenter, case-control study, we recruited 120 patients with PPA (52 non-fluent, 31 semantic, and 32 logopenic variants; and 5 GRN-related PPA) as well as 89 controls from three centers. The 3-Tesla MRI protocol included structural and diffusion-weighted sequences. Disease severity was assessed with the Clinical Dementia Rating scale. Cortical thickness and cortical mean diffusivity were computed using a surface-based approach.ResultsThe comparison between each PPA variant and controls revealed cortical mean diffusivity increases and cortical thinning in overlapping regions, reflecting the canonical loci of neurodegeneration of each variant. Importantly, cortical mean diffusivity increases also expanded to other PPA-related areas and correlated with disease severity in all PPA groups. Cortical mean diffusivity was also increased in patients with very mild PPA when only minimal cortical thinning was observed and showed a good correlation with measures of disease severity.ConclusionsCortical mean diffusivity shows promise as a sensitive biomarker for the study of the neurodegeneration-related microstructural changes in PPA. Keyword: 2.1 Biological and endogenous factors; Acquired Cognitive Impairment; Aging; Alzheimer's disease; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Alzheimer’s disease; Aphasia; Biomedical Imaging; Brain Disorders; Case-Control Studies; Clinical Research; Dementia; Diffusion; Diffusion Magnetic Resonance Imaging; Frontotemporal Dementia (FTD); Frontotemporal lobar degeneration; Humans; Magnetic resonance; Magnetic Resonance Imaging; Medical and Health Sciences; Neurodegenerative; Neurological; Neurosciences; Primary Progressive; Primary progressive aphasia; Rare Diseases URL: https://escholarship.org/uc/item/4td346vg BASE Hide details 3 Improving the diagnostic accuracy of primary progressive aphasia using cognitive tests Foxe, David Gordon. - : The University of Sydney, 2022. : Faculty of Science, School of Psychology, 2022 BASE Show details 4 A Meta-Analysis of Semantic Memory in Mild Cognitive Impairment Joubert, Sven; Gardy, Ludovic; Didic, Mira... In: ISSN: 1040-7308 ; EISSN: 1573-6660 ; Neuropsychology Review ; https://hal.archives-ouvertes.fr/hal-03015335 ; Neuropsychology Review, Springer Verlag, 2021, ⟨10.1007/s11065-020-09453-5⟩ (2021) BASE Show details 5 Cognitive Impairment in Late-Life Depression: A Comparative Study of Healthy Older People, Late-Life Depression, and Mild Alzheimer's Disease Using Multivariate Base Rates of Low Scores Masse, Caroline; Vandel, Pierre; Sylvestre, Géraldine... In: EISSN: 1664-1078 ; Frontiers in Psychology ; https://hal-univ-fcomte.archives-ouvertes.fr/hal-03630024 ; Frontiers in Psychology, Frontiers, 2021, 12, pp.724731. ⟨10.3389/fpsyg.2021.724731⟩ (2021) BASE Show details 6 Uniform data set language measures for bvFTD and PPA diagnosis and monitoring. Staffaroni, Adam M; Weintraub, Sandra; Rascovsky, Katya... In: Alzheimer's & dementia (Amsterdam, Netherlands), vol 13, iss 1 (2021) BASE Show details 7 Social Behavior Observer Checklist: Patterns of Spontaneous Behaviors Differentiate Patients With Neurodegenerative Disease From Healthy Older Adults. Rankin, Katherine P; Toller, Gianina; Gavron, Lauren. - : eScholarship, University of California, 2021 BASE Show details 8 Resting functional connectivity in the semantic appraisal network predicts accuracy of emotion identification. Yang, Winson FZ; Toller, Gianina; Shdo, Suzanne. - : eScholarship, University of California, 2021 BASE Show details 9 Uniform data set language measures for bvFTD and PPA diagnosis and monitoring. Staffaroni, Adam M; Weintraub, Sandra; Rascovsky, Katya... In: Alzheimer's & dementia (Amsterdam, Netherlands), vol 13, iss 1 (2021) BASE Show details 10 Asian Americans and Pacific Islanders' perspectives on participating in the CARE recruitment research registry for Alzheimer's disease and related dementias, aging, and caregiving research. Ta Park, Van; Grill, Joshua D; Zhu, Jeanette... In: Alzheimer's & dementia (New York, N. Y.), vol 7, iss 1 (2021) BASE Show details 11 APOE alleles' association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL). Granot-Hershkovitz, Einat; Tarraf, Wassim; Kurniansyah, Nuzulul... In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 17, iss 3 (2021) BASE Show details 12 The New Face of Caregiving: Multidimensional Factors of Caregiver Burden Among Young Adult Caregivers Demko, Courtney Marie. - : eScholarship, University of California, 2021 BASE Show details 13 Data for: Correlates of Anomia in non-semantic Variants of Primary Progressive Aphasia Converge over Time ... Leyton, Cristian. - : Mendeley, 2021 BASE Show details 14 Data for: Correlates of Anomia in non-semantic Variants of Primary Progressive Aphasia Converge over Time ... Leyton, Cristian. - : Mendeley, 2021 BASE Show details 15 Student Project: Semantic Priming and Alzheimer's Disease (Oliver Rimkus)- Template ... Nowak, Alexander. - : Open Science Framework, 2021 BASE Show details 16 Aprendre idiomes de gran crea connexions neuronals beneficioses Bueno i Torrens, David, 1965-. - : Edició de Premsa Periòdica Ara, 2021 BASE Show details 17 Deterioros lingüísticos asociados a un caso clínico de demencia tipo alzhéimer ; Language impairments associated with a clinical case of Alzheimer’s dementia Jiménez Ruiz, Juan Luis; Palenzuela Sánchez, Ángeles. - : Universidad Nacional Autónoma de México, 2021 BASE Show details 18 Network Effects Of Reduced Audibility (NEORA) and its Significance for Cognitive Decline Alcock, C. - : University of Exeter, 2021. : College of Engineering, Mathematics, and Physical Sciences, 2021 BASE Show details 19 Edinburgh Cognitive and Behavioural ALS Screen (ECAS) in the assessment of early onset dementia De Icaza Valenzuela, Mónica Mariana. - : The University of Edinburgh, 2021 BASE Show details 20 Distinctive Oculomotor Behaviors in Alzheimer's Disease and Frontotemporal Dementia Lage, Carmen; López-García, Sara; Bejanin, Alexandre. - 2021 BASE Show details Page: 1 2 3 4 5...12

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