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Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia ...
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Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia
In: Translational Psychiatry, 9 (1) (2019)
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Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia
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Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia
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5
Genome-wide screening for DNA variants associated with reading and language traits
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A cross-linguistic evaluation of script-specific effects on fMRI lateralization in late second language readers
Koyama, Maki S.; Stein, John F.; Stoodley, Catherine J.. - : Frontiers Media S.A., 2014
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Increased prevalence of sex chromosome aneuploidies in specific language impairment and dyslexia
Abstract: Aim: Sex chromosome aneuploidies increase the risk of spoken or written language disorders but individuals with specific language impairment (SLI) or dyslexia do not routinely undergo cytogenetic analysis. We assess the frequency of sex chromosome aneuploidies in individuals with language impairment or dyslexia. Method: Genome-wide single nucleotide polymorphism genotyping was performed in three sample sets: a clinical cohort of individuals with speech and language deficits (87 probands: 61 males, 26 females; age range 4 to 23 years), a replication cohort of individuals with SLI, from both clinical and epidemiological samples (209 probands: 139 males, 70 females; age range 4 to 17 years), and a set of individuals with dyslexia (314 probands: 224 males, 90 females; age range 7 to 18 years). Results: In the clinical language-impaired cohort, three abnormal karyotypic results were identified in probands (proband yield 3.4%). In the SLI replication cohort, six abnormalities were identified providing a consistent proband yield (2.9%). In the sample of individuals with dyslexia, two sex chromosome aneuploidies were found giving a lower proband yield of 0.6%. In total, two XYY, four XXY (Klinefelter syndrome), three XXX, one XO (Turner syndrome), and one unresolved karyotype were identified. Interpretation: The frequency of sex chromosome aneuploidies within each of the three cohorts was increased over the expected population frequency (approximately 0.25%) suggesting that genetic testing may prove worthwhile for individuals with language and literacy problems and normal non-verbal IQ. Early detection of these aneuploidies can provide information and direct the appropriate management for individuals. © 2013 The Authors. Developmental Medicine & Child Neurology published by John Wiley & Sons Ltd on behalf of Mac Keith Press.
URL: https://publications.aston.ac.uk/id/eprint/21009/1/Increased_prevalence_of_sex_chromosome_aneuploidies_in_specific_language_impairment_and_dyslexia.pdf
https://publications.aston.ac.uk/id/eprint/21009/
https://doi.org/10.1111/dmcn.12294
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8
Dynamic visual perception and reading development in Chinese school children
In: Annals of dyslexia. - New York, NY : Springer 61 (2011) 2, 161-176
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9
The neurobiological basis of dyslexia
In: The SAGE handbook of dyslexia. - Los Angeles, Calif. : SAGE (2008), 53-76
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10
Balancing and pointing tasks in dyslexic and control adults
In: Dyslexia. - Bracknell : British Dyslexia Association 12 (2006) 4, 276-288
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11
Auditory event-related potentials differ in dyslexics even when auditory psychophysical performance is normal
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12
Dyslexia in context : research, policy and practice
Andersson, Bodil (Mitarb.); Stein, John F. (Mitarb.); Lyon, G. Reid (Mitarb.). - London [u.a.] : Whurr, 2004
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13
Two visual motion processing deficits in developmental dyslexia associated with different reading skills deficits
In: Journal of cognitive neuroscience. - Cambridge, Mass. : MIT Press Journals 16 (2004) 4, 528-540
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14
Two Visual Motion Processing Deficits in Developmental Dyslexia Associated with Different Reading Skills Deficits
In: Journal of cognitive neuroscience. - Cambridge, Mass. : MIT Press Journals 16 (2004) 4, 528-540
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15
The perception of 'sine-wave speech' by adults with developmental dyslexia
In: Journal of speech, language, and hearing research. - Rockville, Md. : American Speech-Language-Hearing Association 46 (2003) 1, 68-79
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OLC Linguistik
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16
Commentaries on the Reynolds et al. article and authors response. "Evaluation of an exercise-based treatment for children with reading difficulties, Dyslexia 9.2003,1, S. 48-71" [Rezension]
Miles, Thomas R. (Mitarb.); Peer, Lindsay (Mitarb.); Stein, John F. (Mitarb.)...
In: Dyslexia. - Bracknell : British Dyslexia Association 9 (2003) 2, 122-135
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17
Impaired sensitivity to dynamic stimuli in poor readers of a regular orthography
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 87 (2003) 2, 259-266
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18
Impaired sensitivity to dynamic stimuli in poor readers of a regular orthography
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 87 (2003) 2, 259-266
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19
On the relationship between dynamic visual and auditory processing and literacy skills : results from a large primary-school study
In: Dyslexia. - Bracknell : British Dyslexia Association 8 (2002) 4, 204-225
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20
The dyslexia ecosystem : commentaries
Stein, John F. (Mitarb.); Miles, Thomas R. (Mitarb.); Fawcett, Angela (Mitarb.)
In: Dyslexia. - Bracknell : British Dyslexia Association 8 (2002) 3, 178-182
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