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Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia ...
Abstract: Developmental dyslexia (DD) is one of the most prevalent learning disorders, with high impact on school and psychosocial development and high comorbidity with conditions like attention-deficit hyperactivity disorder (ADHD), depression, and anxiety. DD is characterized by deficits in different cognitive skills, including word reading, spelling, rapid naming, and phonology. To investigate the genetic basis of DD, we conducted a genome-wide association study (GWAS) of these skills within one of the largest studies available, including nine cohorts of reading-impaired and typically developing children of European ancestry (N = 2562–3468). We observed a genome-wide significant effect (p < 1 × 10−8) on rapid automatized naming of letters (RANlet) for variants on 18q12.2, within MIR924HG (micro-RNA 924 host gene; rs17663182 p = 4.73 × 10−9), and a suggestive association on 8q12.3 within NKAIN3 (encoding a cation transporter; rs16928927, p = 2.25 × 10−8). rs17663182 (18q12.2) also showed genome-wide significant ... : Translational Psychiatry, 9 (1) ...
URL: http://hdl.handle.net/20.500.11850/325580
https://dx.doi.org/10.3929/ethz-b-000325580
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2
Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia
In: Translational Psychiatry, 9 (1) (2019)
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3
Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia
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Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia
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Genome-wide screening for DNA variants associated with reading and language traits
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6
A cross-linguistic evaluation of script-specific effects on fMRI lateralization in late second language readers
Koyama, Maki S.; Stein, John F.; Stoodley, Catherine J.. - : Frontiers Media S.A., 2014
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7
Increased prevalence of sex chromosome aneuploidies in specific language impairment and dyslexia
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8
Dynamic visual perception and reading development in Chinese school children
In: Annals of dyslexia. - New York, NY : Springer 61 (2011) 2, 161-176
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OLC Linguistik
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9
The neurobiological basis of dyslexia
In: The SAGE handbook of dyslexia. - Los Angeles, Calif. : SAGE (2008), 53-76
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10
Balancing and pointing tasks in dyslexic and control adults
In: Dyslexia. - Bracknell : British Dyslexia Association 12 (2006) 4, 276-288
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OLC Linguistik
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11
Auditory event-related potentials differ in dyslexics even when auditory psychophysical performance is normal
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12
Dyslexia in context : research, policy and practice
Andersson, Bodil (Mitarb.); Stein, John F. (Mitarb.); Lyon, G. Reid (Mitarb.). - London [u.a.] : Whurr, 2004
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UB Frankfurt Linguistik
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13
Two visual motion processing deficits in developmental dyslexia associated with different reading skills deficits
In: Journal of cognitive neuroscience. - Cambridge, Mass. : MIT Press Journals 16 (2004) 4, 528-540
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14
Two Visual Motion Processing Deficits in Developmental Dyslexia Associated with Different Reading Skills Deficits
In: Journal of cognitive neuroscience. - Cambridge, Mass. : MIT Press Journals 16 (2004) 4, 528-540
OLC Linguistik
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15
The perception of 'sine-wave speech' by adults with developmental dyslexia
In: Journal of speech, language, and hearing research. - Rockville, Md. : American Speech-Language-Hearing Association 46 (2003) 1, 68-79
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OLC Linguistik
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16
Commentaries on the Reynolds et al. article and authors response. "Evaluation of an exercise-based treatment for children with reading difficulties, Dyslexia 9.2003,1, S. 48-71" [Rezension]
Miles, Thomas R. (Mitarb.); Peer, Lindsay (Mitarb.); Stein, John F. (Mitarb.)...
In: Dyslexia. - Bracknell : British Dyslexia Association 9 (2003) 2, 122-135
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17
Impaired sensitivity to dynamic stimuli in poor readers of a regular orthography
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 87 (2003) 2, 259-266
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18
Impaired sensitivity to dynamic stimuli in poor readers of a regular orthography
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 87 (2003) 2, 259-266
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19
On the relationship between dynamic visual and auditory processing and literacy skills : results from a large primary-school study
In: Dyslexia. - Bracknell : British Dyslexia Association 8 (2002) 4, 204-225
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20
The dyslexia ecosystem : commentaries
Stein, John F. (Mitarb.); Miles, Thomas R. (Mitarb.); Fawcett, Angela (Mitarb.)
In: Dyslexia. - Bracknell : British Dyslexia Association 8 (2002) 3, 178-182
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