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1	Predicting language treatment response in bilingual aphasia using neural network-based patient models
	Grasemann, Uli; Peñaloza, Claudia; Dekhtyar, Maria; Miikkulainen, Risto; Kiran, Swathi
	In: Sci Rep (2021)
	Abstract: Predicting language therapy outcomes in bilinguals with aphasia (BWA) remains challenging due to the multiple pre- and poststroke factors that determine the deficits and recovery of their two languages. Computational models that simulate language impairment and treatment outcomes in BWA can help predict therapy response and identify the optimal language for treatment. Here we used the BiLex computational model to simulate the behavioral profile of language deficits and treatment response of a retrospective sample of 13 Spanish-English BWA who received therapy in one of their languages. Specifically, we simulated their prestroke naming ability and poststroke naming impairment in each language, and their treatment response in the treated and the untreated language. BiLex predicted treatment effects accurately and robustly in the treated language and captured different degrees of cross-language generalization in the untreated language in BWA. Our cross-validation approach further demonstrated that BiLex generalizes to predict treatment response for patients whose data were not used in model training. These findings support the potential of BiLex to predict therapy outcomes for BWA and suggest that computational modeling may be helpful to guide individually tailored rehabilitation plans for this population.
	Keyword: Article
	URL: https://doi.org/10.1038/s41598-021-89443-6 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131385/
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2	Characterizing Dynamic Word Meaning Representations in the Brain ...
	The 28th International Conference on Computational Linguistics 2020; Aguirre-Celis, Nora; Miikkulainen, Risto. - : Underline Science Inc., 2020
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3	BiLex: A computational approach to the effects of age of acquisition and language exposure on bilingual lexical access
	Peñaloza, Claudia; Grasemann, Uli; Dekhtyar, Maria. - 2019
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4	Identifying lexical relationships and entailments with distributional semantics
	Roller, Stephen Creig. - 2017
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5	A computational account of bilingual aphasia rehabilitation*
	KIRAN, SWATHI; GRASEMANN, ULI; SANDBERG, CHALEECE...
	In: Bilingualism. - Cambridge : Univ. Press 16 (2013) 2, 325-342
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6	A Computational Account of Bilingual Aphasia Rehabilitation
	Kiran, Swathi; Grasemann, Uli; Sandberg, Chaleece. - 2012
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7	A computational model of language pathology in schizophrenia
	Grasemann, Hans Ulrich. - 2011
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8	Simulating Bilingual Aphasia Rehabilitation: Evidence from a computational model
	Kiran, Swathi; Grasemann, Uli; Sandberg, Chaleece. - 2011
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9	Rehabilitation and cross-language transfer in bilingual aphasia: towards a computational model
	Grasemann, Uli; Sandberg, Chaleece; Kiran, Swathi. - : BioMed Central, 2010
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10	Rehabilitation and cross-language transfer in bilingual aphasia: towards a computational model
	Grasemann, Uli; Sandberg, Chaleece; Kiran, Swathi. - : BMC Neuroscience, 2010
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11	Semantic boost on episodic associations: an empirically-based computational model
	Miikkulainen, Risto; Bentin, Shlomo; Silberman, Yaron
	In: Cognitive science. - Hoboken, NJ : Wiley-Blackwell 31 (2007) 4, 645-671
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12	Semantic Boost on Episodic Associations: An Empirically‐Based Computational Model
	Silberman, Yaron; Bentin, Shlomo; Miikkulainen, Risto
	In: Cognitive science. - Hoboken, NJ : Wiley-Blackwell 31 (2007) 4, 645-671
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13	Effects of Acquisition Rate on Emergent Structure in Phonological Development
	Redford, Melissa A; Miikkulainen, Risto
	In: Language. - Washington, DC : Linguistic Society of America 83 (2007) 4, 737-769
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14	Effects of acquisition rate on emergent structure in phonological development
	Redford, Melissa A.; Miikkulainen, Risto
	In: Language. - Washington, DC : Linguistic Society of America 83 (2007) 4, 737-769
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15	Developing navigation behavior through self-organizing distinctive-state abstraction
	Provost, Jefferson; Kuipers, Benjamin; Miikkulainen, Risto
	In: Connection science. - Abingdon, Oxfordshire : Taylor & Francis 18 (2006) 2, 159-172
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16	Incremental nonmonotonic parsing through semantic self-organization
	Mayberry, Marshall Reeves. - 2003
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17	Constrained emergence of universals and variation in syllable systems
	Redford, Melissa A.; Chen, Chun Chi; Miikkulainen, Risto
	In: Language and speech. - London [u.a.] : Sage Publ. 44 (2001) 1, 27-56
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18	Constrained Emergence of Universals and Variation in Syllable Systems
	Redford, Melissa A.; Chen, Chun Chi; Miikkulainen, Risto
	In: Language and speech. - London [u.a.] : Sage Publ. 44 (2001) 1, 27-56
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19	Constrained Emergence of Universals and Variation in Syllable Systems [<Journal>]
	Chen, Chun Chi; Redford, Melissa A.; Miikkulainen, Risto. - : Kingston Press
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20	Semantic Effect on Episodic Associations
	Silberman, Yaron; Miikkulainen, Risto; Bentin, Shlomo. - : Lawrence Erlbaum Associates, 2001
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