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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 4 5...10 Hits 1 – 20 of 198 1 Attentional abilities constrain language development: A cross-syndrome infant/toddler study D'Souza, Dean; D'Souza, Hana; Jones, Emily. - : Wiley, 2020 BASE Show details 2 Sleep is atypical across neurodevelopmental disorders in infants and toddlers: A cross-syndrome study Karmiloff-Smith, Annette; Plunkett, Kim; Horváth, Klára. - : Elsevier, 2020 BASE Show details 3 Down syndrome and parental depression: a double hit on early expressive language development D'Souza, Hana; Lathan, A.; Karmiloff Smith, Annette. - : Elsevier, 2020 BASE Show details 4 Attentional abilities constrain language development: a cross-syndrome infant/toddler study D'souza, Dean; D'Souza, Hana; Jones, Emily J.H.. - : Wiley, 2020 BASE Show details 5 A multi-level developmental approach to exploring individual differences in Down syndrome: genes, brain, behaviour, and environment Thomas, Michael; Ojinaga Alfageme, Olatz; D'Souza, H.. - : Elsevier, 2020 BASE Show details 6 Health comorbidities and cognitive abilities across the lifespan in Down syndrome. ... Startin, Carla M; D'Souza, Hana; Ball, George. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 7 A multi-level developmental approach to exploring individual differences in Down syndrome: genes, brain, behaviour, and environment. ... Thomas, Michael SC; Ojinaga Alfageme, Olatz; D'Souza, Hana. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 8 Down syndrome and parental depression: A double hit on early expressive language development. ... D'Souza, Hana; Lathan, Amanda; Karmiloff-Smith, Annette. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 9 Down syndrome and parental depression: A double hit on early expressive language development. D'Souza, Hana; Lathan, Amanda; Karmiloff-Smith, Annette. - : Elsevier BV, 2020. : Res Dev Disabil, 2020 BASE Show details 10 A multi-level developmental approach to exploring individual differences in Down syndrome: genes, brain, behaviour, and environment. Thomas, Michael SC; Ojinaga Alfageme, Olatz; D'Souza, Hana. - : Research in developmental disabilities, 2020 BASE Show details 11 Health comorbidities and cognitive abilities across the lifespan in Down syndrome. Startin, Carla M; D'Souza, Hana; Ball, George. - : Springer Science and Business Media LLC, 2020. : J Neurodev Disord, 2020 BASE Show details 12 Down syndrome and parental depression: A double hit on early expressive language development D’Souza, Hana; Lathan, Amanda; Karmiloff-Smith, Annette. - : Pergamon Press, 2020 BASE Show details 13 A multi-level developmental approach to exploring individual differences in Down syndrome: genes, brain, behaviour, and environment Thomas, Michael S.C.; Ojinaga Alfageme, Olatz; D’Souza, Hana; Patkee, Prachi A.; Rutherford, Mary A.; Mok, Kin Y.; Hardy, John; Karmiloff-Smith, Annette In: Res Dev Disabil (2020) Abstract: In this article, we focus on the causes of individual differences in Down syndrome (DS), exemplifying the multi-level, multi-method, lifespan developmental approach advocated by Karmiloff-Smith (1998, 2009, 2012, 2016). We evaluate the possibility of linking variations in infant and child development with variations in the (elevated) risk for Alzheimer’s disease (AD) in adults with DS. We review the theoretical basis for this argument, considering genetics, epigenetics, brain, behaviour and environment. In studies 1 and 2, we focus on variation in language development. We utilise data from the MacArthur-Bates Communicative Development Inventories (CDI; Fenson et al., 2007), and Mullen Scales of Early Learning (MSEL) receptive and productive language subscales (Mullen, 1995) from 84 infants and children with DS (mean age 2;3, range 0;7 to 5;3). As expected, there was developmental delay in both receptive and expressive vocabulary and wide individual differences. Study 1 examined the influence of an environmental measure (socio-economic status as measured by parental occupation) on the observed variability. SES did not predict a reliable amount of the variation. Study 2 examined the predictive power of a specific genetic measure (apolipoprotein APOE genotype) which modulates risk for AD in adulthood. There was no reliable effect of APOE genotype, though weak evidence that development was faster for the genotype conferring greater AD risk (ε4 carriers), consistent with recent observations in infant attention (D’Souza, Mason et al., 2020). Study 3 considered the concerted effect of the DS genotype on early brain development. We describe new magnetic resonance imaging methods for measuring prenatal and neonatal brain structure in DS (e.g., volumes of supratentorial brain, cortex, cerebellar volume; Patkee et al., 2019). We establish the methodological viability of linking differences in early brain structure to measures of infant cognitive development, measured by the MSEL, as a potential early marker of clinical relevance. Five case studies are presented as proof of concept, but these are as yet too few to discern a pattern. Keyword: Article URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438975/ http://www.ncbi.nlm.nih.gov/pubmed/32653761 https://doi.org/10.1016/j.ridd.2020.103638 BASE Hide details 14 Narrowing Perceptual Sensitivity to the Native Language in Infancy: Exogenous Influences on Developmental Timing Elsabbagh, Mayada; Hohenberger, Annette; Campos, Ruth. - : Saarländische Universitäts- und Landesbibliothek, 2018 BASE Show details 15 Fractionating nonword repetition: the contributions of short-term memory and oromotor praxis are different Carey, Daniel; Karmiloff-Smith, Annette; Krishnan, Saloni. - : Public Library of Science, 2017 BASE Show details 16 Intelligence as a developing function: a Neuroconstructivist approach Rinaldi, L.; Karmiloff-Smith, Annette. - : MDPI, 2017 BASE Show details 17 Syndromic Autism: progressing beyond current levels of description Glennon, Jennifer M.; Karmiloff-Smith, Annette; Thomas, Michael S.C.. - : Springer, 2017 BASE Show details 18 Distinct profiles of information-use characterize identity judgments in children and low-expertise adults Ewing, Louise; Karmiloff-Smith, Annette; Farran, E.K.. - : American Psychological Association, 2017 BASE Show details 19 Precursors to language development in typically and atypically developing infants and toddlers: the importance of embracing complexity D'Souza, Hana; D'Souza, Dean; Karmiloff-Smith, Annette. - : Cambridge Journals, 2017 BASE Show details 20 Fractionating nonword repetition:The contributions of short-term memory and oromotor praxis are different Krishnan, Saloni; Alcock, Katherine J.; Carey, Daniel. - 2017 BASE Show details Page: 1 2 3 4 5...10

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