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1
Applying speech technologies to assess verbal memory in patients with serious mental illness
Abstract: Verbal memory deficits are some of the most profound neurocognitive deficits associated with schizophrenia and serious mental illness in general. As yet, their measurement in clinical settings is limited to traditional tests that allow for limited administrations and require substantial resources to deploy and score. Therefore, we developed a digital ambulatory verbal memory test with automated scoring, and repeated self-administration via smart devices. One hundred and four adults participated, comprising 25 patients with serious mental illness and 79 healthy volunteers. The study design was successful with high quality speech recordings produced to 92% of prompts (Patients: 86%, Healthy: 96%). The story recalls were both transcribed and scored by humans, and scores generated using natural language processing on transcriptions were comparable to human ratings (R = 0.83, within the range of human-to-human correlations of R = 0.73–0.89). A fully automated approach that scored transcripts generated by automatic speech recognition produced comparable and accurate scores (R = 0.82), with very high correlation to scores derived from human transcripts (R = 0.99). This study demonstrates the viability of leveraging speech technologies to facilitate the frequent assessment of verbal memory for clinical monitoring purposes in psychiatry.
Keyword: Article
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066153/
https://doi.org/10.1038/s41746-020-0241-7
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2
24.4 MOVING SPEECH TECHNOLOGY METHODS OUT OF THE LABORATORY: PRACTICAL CHALLENGES AND CLINICAL TRANSLATION OPPORTUNITIES FOR PSYCHIATRY
Holmlund, Terje; Foltz, Peter W; Cohen, Alex S. - : Oxford University Press, 2019
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3
The effect of limited cognitive resources on communication disturbances in serious mental illness
In: PMC (2017)
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4
Can RDoC Help Find Order in Thought Disorder?
Cohen, Alex S.; Le, Thanh P.; Fedechko, Taylor L.. - : Oxford University Press, 2017
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5
The effect of limited cognitive resources on communication disturbances in serious mental illness
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6
An examination of the language construct in NIMH's research domain criteria: Time for reconceptualization!
Elvevåg, Brita; Cohen, Alex S.; Wolters, Maria K.. - : John Wiley and Sons Inc., 2016
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7
What do we really know about blunted vocal affect and alogia? A meta-analysis of objective assessments
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8
The Normalities and Abnormalities Associated with Speech in Psychometrically-Defined Schizotypy
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9
Speech Deficits in Serious mental Illness: A Cognitive Resource Issue?
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10
Authentic interactive reenactment of cultural heritage with 3D virtual worlds and artificial intelligence
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11
Computerized Measurement of Negative Symptoms in Schizophrenia
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