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21
Higher blood cadmium level is associated with greater cognitive decline in rural Chinese adults aged 65 or older
In: Sci Total Environ (2020)
Abstract: Cadmium (Cd) exposure has been reported to have neurotoxic effects in animal studies and associated with increased Alzheimer’s Disease mortality and lower cognitive function in cross-sectional and case-control studies. However, no results from longitudinal studies on Cd and cognitive decline are available. In this prospective cohort study, we recruited 1867 participants aged 65 years or older from rural areas in China, blood Cd and cognitive function were measured at baseline (2010–2012), and 1554 participants completed cognitive function tests during a 3-year follow-up (2013–2015). Cognitive function was evaluated using nine standardized cognitive tests: The Community Screening Instrument for Dementia, the CERAD Word List Learning, Word list recall, IU Story Recall, Animal Fluency Test, Boston Naming Test, Stick Design, Delayed Stick Design and the IU Token Test. Analysis of covariance models and logistic regression models were used to determine the association between Cd and standardized cognitive decline adjusting for covariates. The median blood Cd concentration of this study population was 2.12 μg/L, and the interquartile range was 1.42–4.64 μg/L. Significant association of higher Cd levels with lower cognitive scores were observed in five individual cognitive tests (Delayed Stick Design, Boston Naming Test, CERAD Word List Learning Test, Word List Recall Test and IU Story Recall Test) and the composite cognitive score adjusting for multi-covariates at baseline. Higher Cd levels were significantly associated with greater 3-year cognitive decline in Delayed Stick Design Test, Boston Naming Test, IU Token Test, Word List Recall Test and Composite cognitive score. For these cognitive tests, participants in the top two Cd quartile group had significantly greater decline than those in the lowest Cd quartile group, while the two lowest Cd quartile groups were not significantly different. Our findings suggest that higher Cd exposure is associated with greater cognitive decline in older Chinese adults.
Keyword: Article
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775354/
https://doi.org/10.1016/j.scitotenv.2020.144072
http://www.ncbi.nlm.nih.gov/pubmed/33280862
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22
Literacy Development in Canadian French Immersion Students: The Role of Oral Language
Krenca, Klaudia. - 2020
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23
Acoustic-Prosodic and Lexical Cues to Deception and Trust: Deciphering How People Detect Lies
In: Transactions of the Association for Computational Linguistics, Vol 8, Pp 199-214 (2020) (2020)
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24
Evaluating the Oral Language Skills of English-Stream and French Immersion Students: Are the CLB/NCLC Applicable?
In: Canadian Journal of Applied Linguistics; Vol. 23 No. 2 (2020): Special Issue: The Canadian National Frameworks for English and French Language Proficiency: Application, Implication, and Impact; 118-140 ; Revue canadienne de linguistique appliquée; Vol. 23 No. 2 (2020): Numéro spécial : Niveaux de compétence linguistique canadiens pour la compétence langagière en français et en anglais : impact, application et implication; 118-140 ; 1920-1818 ; 1481-868X (2020)
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25
Onset Age of Language Acquisition Effects in a Foreign Language Context: Evidence from Chinese–English Bilingual Children [<Journal>]
Xue, Jin [Verfasser]; Hu, Xiaolan [Verfasser]; Yan, Rong [Verfasser].
DNB Subject Category Language
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26
Phonological specificity relates to phonological awareness and reading ability in English–French bilingual children [<Journal>]
Krenca, Klaudia [Verfasser]; Segers, Eliane [Verfasser]; Chen, Xi [Verfasser].
DNB Subject Category Language
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27
English phonological specificity predicts early French reading difficulty in emerging bilingual children [<Journal>]
Krenca, Klaudia [Verfasser]; Gottardo, Alexandra [Verfasser]; Geva, Esther [Verfasser].
DNB Subject Category Language
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28
Examining Chinese vocabulary knowledge in Taiwanese first- and second graders using confirmatory factor analysis [<Journal>]
Chen, Xi [Verfasser]; Koh, Poh Wee [Verfasser]; Ku, Yu-Min [Verfasser]
DNB Subject Category Language
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29
Visual search and reading comprehension in Chinese children: the mediation of word detection skill [<Journal>]
Liu, Duo [Verfasser]; Chen, Xi [Verfasser]
DNB Subject Category Language
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30
MOESM1 of A community-based comprehensive intervention to reduce syphilis infection among low-fee female sex workers in China: a matched-pair, community-based randomized study ...
Dong, Wei; Zhou, Chu; Rou, Ke-Ming. - : figshare, 2019
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31
MOESM1 of A community-based comprehensive intervention to reduce syphilis infection among low-fee female sex workers in China: a matched-pair, community-based randomized study ...
Dong, Wei; Zhou, Chu; Rou, Ke-Ming. - : figshare, 2019
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32
The Role of Reading Fluency in Predicting Reading Proficiency Among French Immersion Elementary Students in Canada
Lee, Kathleen. - 2019
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33
The Direct and Indirect Effects of Syntactic Awareness on French Reading Comprehension in French Immersion Students
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34
The Successes and Challenges of Syrian Refugee Families in Canada: A Follow-Up Study
Shamim, Abir. - 2019
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35
Morphological awareness and literacy in second language learners: a cross-language perspective [<Journal>]
Chen, Xi [Verfasser]; Schwartz, Mila [Sonstige]
DNB Subject Category Language
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36
An emergent interaction between reading fluency and vocabulary in the prediction of reading comprehension among French immersion elementary students [<Journal>]
Lee, Kathleen [Verfasser]; Chen, Xi [Verfasser]
DNB Subject Category Language
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37
Becoming bilingual readers: Examining orthographic processing in learning to read English and French
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38
Vocalizing Natural Sounds in Another Language: Onomatopoeia Translation in Four English Reditions of the Shijing
Chen, Xi. - : The University of Queensland, School of Languages and Cultures, 2018
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39
The roles of metalinguistic skills in Chinese–English biliteracy development [<Journal>]
Luo, Yang Cathy [Verfasser]; Chen, Xi [Sonstige]; Koh, Poh Wee [Sonstige].
DNB Subject Category Language
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40
Models of English and Chinese word reading for adolescent Chinese–English bilinguals [<Journal>]
Gottardo, Alexandra [Verfasser]; Jia, Fanli [Sonstige]; Koh, Poh Wee [Sonstige].
DNB Subject Category Language
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