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Hits 1 – 20 of 534
1
Educação em contexto migratório: desafios para o ensino da língua portuguesa a imigrantes e/ou refugiados
Hartwig, Fátima Bandeira
. - 2022
BASE
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2
O topónimo "Fajã": um património linguístico da macaronésia
Gouveia, Gabriel Jardim
. - 2022
BASE
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3
Interculturalidade e plurilinguismo nos discursos e práticas de educação e formação em contextos pós-coloniais de língua portuguesa
Araujo e Sa, Maria Helena
[Herausgeber];
Ataíde Maciel, Carla Maria
[Herausgeber]. - Brussels : P.I.E-Peter Lang S.A., Éditions Scientifiques Internationales, 2021
DNB Subject Category Language
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4
The Gynecological Papyrus Kahun
Lopes, Maria Helena Trindade
;
Pereira, Ronaldo Guilherme Gurgel
. - : IntechOpen, 2021
BASE
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5
The biological-mechanistic justice system in poetic-linguistic hermeneutics ...
Tredinnick, André Felipe Alves Da Costa
;
Oliveira, Maria Helena Barros De
. - : SciELO journals, 2021
BASE
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6
The biological-mechanistic justice system in poetic-linguistic hermeneutics ...
Tredinnick, André Felipe Alves Da Costa
;
Oliveira, Maria Helena Barros De
. - : SciELO journals, 2021
BASE
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7
Origins and demographic dynamics of Tupí expansion: a genetic tale ...
Santos, Eduardo José Melo Dos
;
Silva, Andréa Luciana Soares Da
;
Ewerton, Paloma Daguer
. - : SciELO journals, 2021
BASE
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8
Origins and demographic dynamics of Tupí expansion: a genetic tale ...
Santos, Eduardo José Melo Dos
;
Silva, Andréa Luciana Soares Da
;
Ewerton, Paloma Daguer
. - : SciELO journals, 2021
BASE
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9
Formação de professores de língua portuguesa para o acolhimento de refugiados
Carvalho, Agenor Francisco de
. - 2021
BASE
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10
A competência intercultural na formação de professores moçambicanos de língua portuguesa: literatura como instrumento de mediação
Monteiro, Ana Catarina Mateus
. - 2021
BASE
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11
O papel da consciência metalinguística na aprendizagem do alemão língua estrangeira
Ribeiro, Gorete Cristina Marques
. - 2021
BASE
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12
Léxico e Sintaxe do Português: edificação e alargamento da consciência e da competência linguísticas por meio da (co)produção de recursos didático-sensoriais
Rodrigues, Letícia Paula Sampaio
. - 2021
BASE
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13
Mathematics for Portuguese students with hearing impairment: an exploratory study of mathematical terms/concepts used in inclusive schools
Saraiva, João Paulo
;
Almendra, Isabel
;
Cruz-Santos, Anabela
. - : Center for Enhancing Knowledge, 2021
BASE
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14
Memorias de Prácticas Profesionales en la Editorial Médica Panamericana: traducción de «Joints. Part 2» de la obra Trail Guide to Movement. Second Edition.
Ramos Orozco, María Helena
. - : Universitat Jaume I, 2021
BASE
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15
Faith, Family, and Social Networks: Effective Strategies for Recruiting Brazilian Immigrants in Maternal and Child Health Research
de Souza Mezzavilla, Raquel
;
de Sá Melo Alves, Amanda
;
Rocha, Thaís C.
...
In: Health Studies Faculty Publications (2021)
BASE
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16
Student perspective on public health training in speech-language-hearing undergraduate programs at public universities in Northeastern Brazil
Maurício Wiering Pinto Telles
;
Letícia Jadsa Lemos Chaves
;
Milyane Cardoso do Nascimento
...
In: Revista CEFAC, Vol 23, Iss 3 (2021) (2021)
BASE
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17
NÚMERO COMPLETO
de PAULA, Maria Helena
In: Linguagem: Estudos e Pesquisas; v. 24 n. 2 (2020); 1-219 ; 2358-1042 (2021)
BASE
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18
EXPEDIENTE
de PAULA, Maria Helena
In: Linguagem: Estudos e Pesquisas; v. 24 n. 2 (2020); 1-12 ; 2358-1042 (2021)
BASE
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19
Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry.
Bigdeli, Tim B
;
Genovese, Giulio
;
Georgakopoulos, Penelope
;
Meyers, Jacquelyn L
;
Peterson, Roseann E
;
Iyegbe, Conrad O
;
Medeiros, Helena
;
Valderrama, Jorge
;
Achtyes, Eric D
;
Kotov, Roman
;
Stahl, Eli A
;
Abbott, Colony
;
Azevedo, Maria Helena
;
Belliveau, Richard A
;
Bevilacqua, Elizabeth
;
Bromet, Evelyn J
;
Byerley, William
;
Carvalho, Celia Barreto
;
Chapman, Sinéad B
;
DeLisi, Lynn E
;
Dumont, Ashley L
;
O'Dushlaine, Colm
;
Evgrafov, Oleg V
;
Fochtmann, Laura J
;
Gage, Diane
;
Kennedy, James L
;
Kinkead, Becky
;
Macedo, Antonio
;
Moran, Jennifer L
;
Morley, Christopher P
;
Dewan, Mantosh J
;
Nemesh, James
;
Perkins, Diana O
;
Purcell, Shaun M
;
Rakofsky, Jeffrey J
;
Scolnick, Edward M
;
Sklar, Brooke M
;
Sklar, Pamela
;
Smoller, Jordan W
;
Sullivan, Patrick F
;
Macciardi, Fabio
;
Marder, Stephen R
;
Gur, Ruben C
;
Gur, Raquel E
;
Braff, David L
;
Consortium on the Genetics of Schizophrenia (COGS) Investigators
;
Nicolini, Humberto
;
Escamilla, Michael A
;
Vawter, Marquis P
;
Sobell, Janet L
;
Malaspina, Dolores
;
Lehrer, Douglas S
;
Buckley, Peter F
;
Rapaport, Mark H
;
Knowles, James A
;
Genomic Psychiatry Cohort (GPC) Consortium
;
Fanous, Ayman H
;
Pato, Michele T
;
McCarroll, Steven A
;
Pato, Carlos N
In: Molecular psychiatry, vol 25, iss 10 (2020)
Abstract:
Schizophrenia is a common, chronic and debilitating neuropsychiatric syndrome affecting tens of millions of individuals worldwide. While rare genetic variants play a role in the etiology of schizophrenia, most of the currently explained liability is within common variation, suggesting that variation predating the human diaspora out of Africa harbors a large fraction of the common variant attributable heritability. However, common variant association studies in schizophrenia have concentrated mainly on cohorts of European descent. We describe genome-wide association studies of 6152 cases and 3918 controls of admixed African ancestry, and of 1234 cases and 3090 controls of Latino ancestry, representing the largest such study in these populations to date. Combining results from the samples with African ancestry with summary statistics from the Psychiatric Genomics Consortium (PGC) study of schizophrenia yielded seven newly genome-wide significant loci, and we identified an additional eight loci by incorporating the results from samples with Latino ancestry. Leveraging population differences in patterns of linkage disequilibrium, we achieve improved fine-mapping resolution at 22 previously reported and 4 newly significant loci. Polygenic risk score profiling revealed improved prediction based on trans-ancestry meta-analysis results for admixed African (Nagelkerke's R2 = 0.032; liability R2 = 0.017; P < 10-52), Latino (Nagelkerke's R2 = 0.089; liability R2 = 0.021; P < 10-58), and European individuals (Nagelkerke's R2 = 0.089; liability R2 = 0.037; P < 10-113), further highlighting the advantages of incorporating data from diverse human populations.
Keyword:
2.1 Biological and endogenous factors
;
African Continental Ancestry Group
;
Biological Sciences
;
Brain Disorders
;
Clinical Research
;
Consortium on the Genetics of Schizophrenia (COGS) Investigators
;
Female
;
Genetic Loci
;
Genetic Predisposition to Disease
;
Genetics
;
Genome-Wide Association Study
;
Genomic Psychiatry Cohort (GPC) Consortium
;
Hispanic Americans
;
Human Genome
;
Humans
;
Male
;
Medical and Health Sciences
;
Mental Health
;
Polymorphism
;
Psychiatry
;
Psychology and Cognitive Sciences
;
Schizophrenia
;
Serious Mental Illness
;
Single Nucleotide
URL:
https://escholarship.org/uc/item/5gk7n9bq
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20
Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry.
Bigdeli, Tim B
;
Genovese, Giulio
;
Georgakopoulos, Penelope
...
In: Molecular psychiatry, vol 25, iss 10 (2020)
BASE
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