1 |
Multivariate genome-wide covariance analyses of literacy, language and working memory skills reveal distinct etiologies
|
|
|
|
In: NPJ Sci Learn (2021)
|
|
BASE
|
|
Show details
|
|
2 |
Polygenic scores and risk prediction for delay (Dale et al., 2020) ...
|
|
|
|
BASE
|
|
Show details
|
|
3 |
Polygenic scores and risk prediction for delay (Dale et al., 2020) ...
|
|
|
|
BASE
|
|
Show details
|
|
4 |
Does the Inclusion of a Genome-Wide Polygenic Score Improve Early Risk Prediction for Later Language and Literacy Delay?
|
|
|
|
BASE
|
|
Show details
|
|
5 |
Does the Inclusion of a Genome-Wide Polygenic Score Improve Early Risk Prediction for Later Language and Literacy Delay?
|
|
|
|
In: J Speech Lang Hear Res (2020)
|
|
BASE
|
|
Show details
|
|
6 |
Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language
|
|
|
|
BASE
|
|
Show details
|
|
7 |
Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language
|
|
|
|
BASE
|
|
Show details
|
|
8 |
Assessing receptive and expressive vocabulary in child language
|
|
|
|
In: Research methods in psycholinguistics and the neurobiology of language (Hoboken, NJ, 2018), p. 40-67
|
|
MPI für Psycholinguistik
|
|
9 |
Grammar Clinical Marker Yields Substantial Heritability for Language Impairments in 16-Year-Old Twins
|
|
|
|
BASE
|
|
Show details
|
|
10 |
The genetic architecture of oral language, reading fluency, and reading comprehension : A twin study from 7 to 16 years
|
|
|
|
BASE
|
|
Show details
|
|
11 |
The Genetic Architecture of Oral Language, Reading Fluency, and Reading Comprehension: A Twin Study From 7 to 16 Years
|
|
|
|
BASE
|
|
Show details
|
|
12 |
Language Differences at 12 Months in Infants Who Develop Autism Spectrum Disorder
|
|
|
|
BASE
|
|
Show details
|
|
13 |
Why does parental language input style predict child language development? A twin study of gene–environment correlation
|
|
|
|
BASE
|
|
Show details
|
|
14 |
Language impairment from 4 to 12 years : : prediction and etiology
|
|
|
|
BASE
|
|
Show details
|
|
15 |
Common variation near ROBO2 is associated with expressive vocabulary in infancy
|
|
St Pourcain, Beate; Cents, Rolieke A. M.; Whitehouse, Andrew J. O.; Haworth, Claire M. A.; Davis, Oliver S. P.; O’Reilly, Paul F.; Roulstone, Susan; Wren, Yvonne; Ang, Qi W.; Velders, Fleur P.; Evans, David M.; Kemp, John P.; Warrington, Nicole M.; Miller, Laura; Timpson, Nicholas J.; Ring, Susan M.; Verhulst, Frank C.; Hofman, Albert; Rivadeneira, Fernando; Meaburn, Emma L.; Price, Thomas S.; Dale, Philip S.; Pillas, Demetris; Yliherva, Anneli; Rodriguez, Alina; Golding, Jean; Jaddoe, Vincent W. V.; Jarvelin, Marjo-Riitta; Plomin, Robert; Pennell, Craig E.; Tiemeier, Henning; Davey Smith, George. - : Nature Publishing Group, 2014
|
|
Abstract:
Twin studies suggest that expressive vocabulary at ~24 months is modestly heritable. However, the genes influencing this early linguistic phenotype are unknown. Here we conduct a genome-wide screen and follow-up study of expressive vocabulary in toddlers of European descent from up to four studies of the EArly Genetics and Lifecourse Epidemiology consortium, analysing an early (15–18 months, ‘one-word stage’, NTotal=8,889) and a later (24–30 months, ‘two-word stage’, NTotal=10,819) phase of language acquisition. For the early phase, one single-nucleotide polymorphism (rs7642482) at 3p12.3 near ROBO2, encoding a conserved axon-binding receptor, reaches the genome-wide significance level (P=1.3 × 10−8) in the combined sample. This association links language-related common genetic variation in the general population to a potential autism susceptibility locus and a linkage region for dyslexia, speech-sound disorder and reading. The contribution of common genetic influences is, although modest, supported by genome-wide complex trait analysis (meta-GCTA h215–18-months=0.13, meta-GCTA h224–30-months=0.14) and in concordance with additional twin analysis (5,733 pairs of European descent, h224-months=0.20).
|
|
Keyword:
C420 Human Genetics; C841 Health Psychology
|
|
URL: https://doi.org/10.1038/ncomms5831 https://eprints.lincoln.ac.uk/id/eprint/22920/ https://eprints.lincoln.ac.uk/id/eprint/22920/1/22920%20ncomms5831.pdf
|
|
BASE
|
|
Hide details
|
|
16 |
Common variation near ROBO2 is associated with expressive vocabulary in infancy
|
|
|
|
BASE
|
|
Show details
|
|
17 |
Genome-Wide Association Study of Receptive Language Ability of 12-Year-Olds
|
|
|
|
BASE
|
|
Show details
|
|
18 |
The high heritability of educational achievement reflects many genetically influenced traits, not just intelligence
|
|
|
|
BASE
|
|
Show details
|
|
19 |
Genome-wide association study of receptive language ability of 12-year-olds
|
|
|
|
BASE
|
|
Show details
|
|
20 |
Common variation near ROBO2 is associated with expressive vocabulary in infancy
|
|
|
|
BASE
|
|
Show details
|
|
|
|