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1
Multivariate genome-wide covariance analyses of literacy, language and working memory skills reveal distinct etiologies
In: NPJ Sci Learn (2021)
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2
Polygenic scores and risk prediction for delay (Dale et al., 2020) ...
Abstract: Purpose: The ability to identify children early in development who are at substantial risk for language/literacy difficulties would have great benefit both for the children and for the educational and therapeutic institutions that serve them. Information that is relatively easily available prior to the age of 3 years, such as late talking, family history of language/literacy difficulties, and socioeconomic status, have some but very limited predictive power. Here, we examine whether the inclusion of a DNA-based genome-wide polygenic score that has been shown to capture children’s genetic propensity for educational attainment (EA3) adds enough prediction to yield a clinically useful score. Method: Data are longitudinal scores of 1,420 children from the Twins Early Development Study, who were assessed at ages 2 and 3 years on language and nonverbal ability and at 12 years of age on oral language, word decoding, and reading comprehension. Five risk factors were examined: expressive vocabulary, nonverbal ability ...
Keyword: 60405 Gene Expression incl. Microarray and other genome-wide approaches; FOS Biological sciences; Language
URL: https://asha.figshare.com/articles/Polygenic_scores_and_risk_prediction_for_delay_Dale_et_al_2020_/12170331
https://dx.doi.org/10.23641/asha.12170331
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3
Polygenic scores and risk prediction for delay (Dale et al., 2020) ...
Dale, Philip S.; Stumm, Sophie Von; Selzam, Saskia. - : ASHA journals, 2020
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4
Does the Inclusion of a Genome-Wide Polygenic Score Improve Early Risk Prediction for Later Language and Literacy Delay?
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5
Does the Inclusion of a Genome-Wide Polygenic Score Improve Early Risk Prediction for Later Language and Literacy Delay?
In: J Speech Lang Hear Res (2020)
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6
Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language
Verhoef, Ellen; Demontis, Ditte; Burgess, Stephen. - : Springer Nature, 2019
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7
Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language
Verhoef, Ellen; Demontis, Ditte; Burgess, Stephen. - : Nature Publishing Group UK, 2019
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8
Assessing receptive and expressive vocabulary in child language
In: Research methods in psycholinguistics and the neurobiology of language (Hoboken, NJ, 2018), p. 40-67
MPI für Psycholinguistik
9
Grammar Clinical Marker Yields Substantial Heritability for Language Impairments in 16-Year-Old Twins
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10
The genetic architecture of oral language, reading fluency, and reading comprehension : A twin study from 7 to 16 years
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11
The Genetic Architecture of Oral Language, Reading Fluency, and Reading Comprehension: A Twin Study From 7 to 16 Years
Tosto, Maria G.; Hayiou-Thomas, Marianna E.; Harlaar, Nicole. - : American Psychological Association, 2017
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12
Language Differences at 12 Months in Infants Who Develop Autism Spectrum Disorder
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13
Why does parental language input style predict child language development? A twin study of gene–environment correlation
Dale, Philip S.; Tosto, Maria Grazia; Hayiou-Thomas, Marianna E.. - : Elsevier Scientific Publishing, 2015
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14
Language impairment from 4 to 12 years : : prediction and etiology
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15
Common variation near ROBO2 is associated with expressive vocabulary in infancy
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16
Common variation near ROBO2 is associated with expressive vocabulary in infancy
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17
Genome-Wide Association Study of Receptive Language Ability of 12-Year-Olds
Harlaar, Nicole; Meaburn, Emma L.; Hayiou-Thomas, Marianna E.. - : American Speech-Language-Hearing Association, 2014
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18
The high heritability of educational achievement reflects many genetically influenced traits, not just intelligence
Krapohl, Eva; Rimfeld, Kaili; Shakeshaft, Nicholas G.. - : National Academy of Sciences, 2014
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19
Genome-wide association study of receptive language ability of 12-year-olds
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20
Common variation near ROBO2 is associated with expressive vocabulary in infancy
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