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Pathways from the Early Language and Communication Environment to Literacy Outcomes at the End of Primary School : The Roles of Language Development and Social Development
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Play and prosociality are associated with fewer externalizing problems in children with developmental language disorder: The role of early language and communication environment. ...
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Pathways from the early language and communication environment to literacy outcomes at the end of primary school: The roles of language development and social development
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Play and Prosociality are Associated with Fewer Externalising Problems in Children with Developmental Language Disorder : The Role of Early Language and Communication Environment
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The Manchester Language Study: Eleven-year-old data for children with developmental language disorders attending language units in England 1999-2001 ...
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The Manchester Language Study: Sixteen-year-old data for children with developmental language disorders who had attended language units in England 2003-2008 ...
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Pathways from the early language and communication environment to literacy outcomes at the end of primary school; the roles of language development and social development
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Using Polygenic Profiles to Predict Variation in Language and Psychosocial Outcomes in Early and Middle Childhood. ...
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Using polygenic profiles to predict variation in language and psychosocial outcomes in early and middle childhood
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Abstract:
Purpose: Children with poor language tend to have worse psychosocial outcomes compared to their typically developing peers. The most common explanations for such adversities focus on developmental psychological processes whereby poor language triggers psychosocial difficulties. Here we investigate the possibility of shared biological effects by considering whether the same genetic variants which are thought to influence language development are also predictors of elevated psychosocial difficulties during childhood. Method: Using data from the UK based Avon Longitudinal Study of Parents and Children (ALSPAC) we created a number of multi-SNP polygenic profile scores, based on language and reading candidate genes (ATP2C2, CMIP, CNTNAP2, DCDC2, FOXP2, & KIAA0319, 1229 SNPs) in a sample of 5,435 children. Results: A polygenic profile score for expressive language (8 years) that was created in a discovery sample (n=2,718), predicted not only expressive language (8 years), but also peer problems (11 years) in a replication sample (n=2,717). Conclusions: These findings provide a proof of concept for the use of such a polygenic approach in child language research when larger datasets become available. Our indicative findings suggest consideration should be given to concurrent intervention targeting both linguistic and psychosocial development as early language interventions may not stave off later psychosocial difficulties in children.
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URL: https://radar.brookes.ac.uk/radar/file/7ccb7924-7fd6-4059-8eae-70a4e36b788a/1/2019_JSLHR-L-19-0001.pdf https://radar.brookes.ac.uk/radar/items/7ccb7924-7fd6-4059-8eae-70a4e36b788a/1/
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Using polygenic profiles to predict variation in language and psychosocial outcomes in early and middle childhood
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The Manchester Language Study initial cohort: seven year old data for children with developmental language disorders attending language units in England 1995-1997 ...
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Using Polygenic Profiles to Predict Variation in Language and Psychosocial Outcomes in Early and Middle Childhood.
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Psycholinguistic and socioemotional characteristics of young offenders: Do language abilities and gender matter?
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Using Polygenic Profiles to Predict Variation in Language and Psychosocial Outcomes in Early and Middle Childhood
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Psycholinguistic and socioemotional characteristics of young offenders: Do language abilities and gender matter?
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Using polygenic profiles to predict variation in language and psychosocial outcomes in early and middle childhood
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Education and employment outcomes of young adults with a history of developmental language disorder
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More or less likely to offend? Young adults with a history of identified Developmental Language Disorder
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Education and employment outcomes of young adults with a history of developmental language disorder
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Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: terminology
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