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Eliciting Requirements for a Diabetes Self-Management Application for Underserved Populations: A Multi-Stakeholder Analysis
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In: International Journal of Environmental Research and Public Health; Volume 19; Issue 1; Pages: 127 (2021)
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Adaptation and psychometric validation of Diabetes Health Profile (DHP-18) in patients with type 2 diabetes in Quito, Ecuador : a cross-sectional study
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Diabetes Apps: Information about COVID-19 and Risk Factors?
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In: J Endocr Soc (2021)
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Dysphonia, arterial hypertension, diabetes mellitus, thyroid diseases, and noise complaints as probable factors associated with hearing loss among teachers
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In: Revista CEFAC, Vol 23, Iss 2 (2021) (2021)
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Effectiveness of Culturally Tailored Interventions for Hispanic Adults with Type 2 Diabetes Mellitus
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Association between diabetes and vestibular dysfunction: an integrative review
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In: Revista CEFAC, Vol 22, Iss 1 (2020) (2020)
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Partial remission and early stages of pediatric type 1 diabetes display immunoregulatory changes. A pilot study
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Villalba Felipe, Adrián; Fonolleda, Mireia; Murillo-Vallés, Marta; Rodríguez-Fernández, Silvia; Ampudia Carrasco, Rosa María; Perna-Barrull, David; Raina, María Belén; Quirant, Bibiana; Planas, Raquel; Teniente Serra, Aina; Bel, J.; Vives Pi, Marta; Universitat Autònoma de Barcelona. - 2019
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Abstract:
Altres ajuts: This work has been funded by the European Regional Development funds (FEDER), and by DiabetesCero Foundation. CIBER of Diabetes and Associated Metabolic Diseases (CIBERDEM) is an initiative from Instituto de Salud Carlos III (Spain). SRF is supported by the Agency for Management of University and Research Grants (AGAUR) of the Generalitat de Catalunya. ; Type 1 diabetes (T1D) is a chronic metabolic disease of unknown etiology that results from β-cell destruction. The onset of the disease, which arises after a long asymptomatic period of autoimmune attack, may be followed by a relapsing and remitting progression, a phenomenon that is most evident during the partial remission phase (PR). This stage lasts for a few months, shows minor requirements of exogenous insulin and could be explained by a recovery of immunological tolerance. This study aims to identify new biomarkers at early stages of pediatric T1D that reflect immunoregulatory changes. To that end, pediatric patients with T1D (n = 52) and age-related control subjects (n = 30) were recruited. Immune response-related molecules and lymphocyte subsets were determined starting at T1D onset and until the second year of progression. Results showed that circulating TGF-β levels decreased during PR, and that betatrophin concentration was increased in all the considered stages without differing among studied checkpoints. Moreover, an increase of regulatory T, B and NK subsets was found during T1D progression, probably reflecting an attempt to restore self-tolerance. By contrast, a reduction in monocyte levels was observed at the early stages of diabetes. The results reveal significant changes in immunological parameters during the different early stages of T1D in children, which could ultimately serve as potential biomarkers to characterize the progression of T1D.
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Keyword:
Angiopoietin-like Proteins; Biomarkers; Body Mass Index; Case-Control Studies; Child; Diabetes Mellitus; Disease Progression; Female; Humans; Immunologic Memory; Lymphocyte Subsets; Male; Monocytes; Peptide Hormones; Pilot Projects; Remission Induction; Transforming Growth Factor beta; Type 1
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URL: https://ddd.uab.cat/record/223023 https://doi.org/10.1016/j.trsl.2019.03.002
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MON-162 Hepatic DNA Damage Induced by ENDS Is Associated with Decreased Levels of NAD+
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SAT-122 A Mobile App to Decrease Risk Factors for Diabetes in Women with Recent GDM
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Language-concordant automated telephone queries to assess medication adherence in a diverse population: a cross-sectional analysis of convergent validity with pharmacy claims.
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In: BMC health services research, vol 18, iss 1 (2018)
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Disparities in Diabetes Care Quality by English Language Preference in Community Health Centers.
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In: Health services research, vol 53, iss 1 (2018)
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Associations of maternal vitamin D deficiency with pregnancy and neonatal complications in developing countries: a systematic review
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Comorbidities, complications and mortality in people of South Asian ethnicity with type 1 diabetes compared with other ethnic groups: a systematic review
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Technology-enhanced consultations in diabetes, cancer, and heart failure: protocol for the qualitative analysis of remote consultations (QuARC) project
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The Next Frontier in Communication and the ECLIPPSE Study: Bridging the Linguistic Divide in Secure Messaging.
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The Next Frontier in Communication and the ECLIPPSE Study: Bridging the Linguistic Divide in Secure Messaging.
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APRN-Led Culturally Tailored Diabetes Self-Management Education (DSME) for Spanish-Speaking Hispanic Americans (SSHAs) ...
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Diabetes Mellitus and the Effects on Auditory Processing
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In: ETSU Faculty Works (2017)
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Health effects of non-nutritive sweeteners: analysis of the research landscape
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In: Nutrition journal. 16 (2017), 55, DOI 10.1186/s12937-017-0278-x, issn: 1475-2891 (2017)
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Zinc status of those with type 2 diabetes compared to a healthy population: A systematic review.
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