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Patient Centered Medical Home Cooking: Community Culinary Workshops for Multidisciplinary Teams
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In: J Prim Care Community Health (2021)
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| 2 |
Partial remission and early stages of pediatric type 1 diabetes display immunoregulatory changes. A pilot study
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Villalba Felipe, Adrián; Fonolleda, Mireia; Murillo-Vallés, Marta; Rodríguez-Fernández, Silvia; Ampudia Carrasco, Rosa María; Perna-Barrull, David; Raina, María Belén; Quirant, Bibiana; Planas, Raquel; Teniente Serra, Aina; Bel, J.; Vives Pi, Marta; Universitat Autònoma de Barcelona. - 2019
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Abstract:
Altres ajuts: This work has been funded by the European Regional Development funds (FEDER), and by DiabetesCero Foundation. CIBER of Diabetes and Associated Metabolic Diseases (CIBERDEM) is an initiative from Instituto de Salud Carlos III (Spain). SRF is supported by the Agency for Management of University and Research Grants (AGAUR) of the Generalitat de Catalunya. ; Type 1 diabetes (T1D) is a chronic metabolic disease of unknown etiology that results from β-cell destruction. The onset of the disease, which arises after a long asymptomatic period of autoimmune attack, may be followed by a relapsing and remitting progression, a phenomenon that is most evident during the partial remission phase (PR). This stage lasts for a few months, shows minor requirements of exogenous insulin and could be explained by a recovery of immunological tolerance. This study aims to identify new biomarkers at early stages of pediatric T1D that reflect immunoregulatory changes. To that end, pediatric patients with T1D (n = 52) and age-related control subjects (n = 30) were recruited. Immune response-related molecules and lymphocyte subsets were determined starting at T1D onset and until the second year of progression. Results showed that circulating TGF-β levels decreased during PR, and that betatrophin concentration was increased in all the considered stages without differing among studied checkpoints. Moreover, an increase of regulatory T, B and NK subsets was found during T1D progression, probably reflecting an attempt to restore self-tolerance. By contrast, a reduction in monocyte levels was observed at the early stages of diabetes. The results reveal significant changes in immunological parameters during the different early stages of T1D in children, which could ultimately serve as potential biomarkers to characterize the progression of T1D.
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Keyword:
Angiopoietin-like Proteins; Biomarkers; Body Mass Index; Case-Control Studies; Child; Diabetes Mellitus; Disease Progression; Female; Humans; Immunologic Memory; Lymphocyte Subsets; Male; Monocytes; Peptide Hormones; Pilot Projects; Remission Induction; Transforming Growth Factor beta; Type 1
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URL: https://ddd.uab.cat/record/223023
https://doi.org/10.1016/j.trsl.2019.03.002
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| 3 |
Benefits of a psychosocial intervention on positive affect and posttraumatic growth for Chinese American breast cancer survivors: a pilot study
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| 4 |
Smartphone-Based Conversational Agents and Responses to Questions About Mental Health, Interpersonal Violence, and Physical Health.
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In: JAMA internal medicine, vol 176, iss 5 (2016)
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| 5 |
Assessing the Value of Structured Analytic Techniques in the U.S. Intelligence Community
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| 6 |
Cross-cultural validation of instruments measuring health beliefs about colorectal cancer screening among Korean Americans.
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In: Journal of Korean Academy of Nursing, vol 45, iss 1 (2015)
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| 7 |
Integrating Family-Based Treatment and Dialectical Behavior Therapy for Adolescent Bulimia Nervosa: Preliminary Outcomes of an Open Pilot Trial.
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In: Eating disorders, vol 23, iss 4 (2015)
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| 9 |
A culturally appropriate intervention to improve health behaviors in Hispanic mother-child dyads.
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In: Childhood obesity (Print), vol 9, iss 2 (2013)
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| 10 |
A culturally appropriate intervention to improve health behaviors in Hispanic mother-child dyads.
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In: Childhood obesity (Print), vol 9, iss 2 (2013)
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| 11 |
United States Special Operations Command's Foreign Language Proficiency Bonus at ILR 1/1+: Initial Review and Recommended Changes to Improve Results and Lower Cost
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In: DTIC (2012)
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| 12 |
New models of self-management education for minority ethnic groups: pilot randomized trial of a story-sharing intervention.
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In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Scopus (http://www.scopus.com/home.url) ; CrossRef (2011)
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| 13 |
Engaging adolescent girls from linguistically diverse and low income backgrounds in school sport : a pilot randomised controlled trial
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| 14 |
Social Awareness and Leader Influence: Development of Classroom and Web-Based Learning Interventions
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In: DTIC (2009)
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| 15 |
Grammar improvement following deep brain stimulation of the subthalamic and the pedunculopontine nuclei in advanced Parkinson's disease: a pilot study
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| 16 |
Grammar improvement following deep brain stimulation of the subthalamic and the pedunculopontine nuclei in advanced Parkinson's disease: a pilot study
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| 17 |
Construction of a Phonotactic Dialect Corpus using Semiautomatic Annotation
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In: DTIC (2007)
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| 18 |
Development of Research Platform for Unmanned Vehicle Controller Design, Evaluation, and Implementation System: From MATLAB to Hardware Based Embedded System
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Ernst, Daniel. - : Digital Commons @ University of South Florida, 2007
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In: Graduate Theses and Dissertations (2007)
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| 19 |
Assessing clinical competence: a pilot project to evaluate the feasibility of a standardized patient -- based practical examination as a component of the Swiss certification process
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In: ISSN: 1424-7860 ; Swiss Medical Weekly, Vol. 136, No 25-26 (2006) pp. 392-9 (2006)
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| 20 |
Mental Models Theory and Military Decision-Marking: A Pilot Experimental Model
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In: DTIC AND NTIS (2003)
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