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Example of Narrative Recall produced by a child with DLD ...
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Example of Narrative Recall produced by a child with DLD ...
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Speech movement variability in people who stutter (Wiltshire et al., 2021) ...
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Speech movement variability in people who stutter (Wiltshire et al., 2021) ...
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Cerebral lateralisation of first and second languages in bilinguals assessed using functional transcranial Doppler ultrasound
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Functional organisation for verb generation in children with developmental language disorder
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In: Neuroimage (2021)
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Asymmetry of Auditory-Motor Speech Processing is Determined by Language Experience
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In: J Neurosci (2021)
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Cerebral lateralisation of first and second languages in bilinguals assessed using functional transcranial Doppler ultrasound
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In: Wellcome Open Res (2021)
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Disruption of speech motor adaptation with repetitive transcranial magnetic stimulation of the articulatory representation in primary motor cortex
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In: Cortex (2021)
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Functional organisation for verb generation in children with developmental language disorder
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Failure of tDCS to modulate motor excitability and speech motor learning
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In: Neuropsychologia (2020)
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Abstract:
Transcranial direct current stimulation (tDCS) modulates cortical excitability in a polarity-specific way and, when used in combination with a behavioural task, it can alter performance. TDCS has the potential, therefore, for use as an adjunct to therapies designed to treat disorders affecting speech, including, but not limited to acquired aphasias and developmental stuttering. For this reason, it is important to conduct studies evaluating its effectiveness and the parameters optimal for stimulation. Here, we aimed to evaluate the effects of bi-hemispheric tDCS over speech motor cortex on performance of a complex speech motor learning task, namely the repetition of tongue twisters. A previous study in older participants showed that tDCS could modulate performance on a similar task. To further understand the effects of tDCS, we also measured the excitability of the speech motor cortex before and after stimulation. Three groups of 20 healthy young controls received: (i) anodal tDCS to the left IFG/LipM1 and cathodal tDCS to the right hemisphere homologue; or (ii) cathodal tDCS over the left and anodal over the right; or (iii) sham stimulation. Participants heard and repeated novel tongue twisters and matched simple sentences before, during and 10 min after the stimulation. One mA tDCS was delivered concurrent with task performance for 13 min. Motor excitability was measured using transcranial magnetic stimulation to elicit motor-evoked potentials in the lip before and immediately after tDCS. The study was double-blind, randomized, and sham-controlled; the design and analysis were pre-registered. Performance on the task improved from baseline to after stimulation but was not significantly modulated by tDCS. Similarly, a small decrease in motor excitability was seen in all three stimulation groups but did not differ among them and was unrelated to task performance. Bayesian analyses provide substantial evidence in support of the null hypotheses in both cases, namely that tongue twister performance and motor excitability were not affected by tDCS. We discuss our findings in the context of the previous positive results for a similar task. We conclude that tDCS may be most effective when brain function is sub-optimal due to age-related declines or pathology. Further study is required to determine why tDCS failed to modulate excitability in the speech motor cortex in the expected ways.
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URL: http://www.ncbi.nlm.nih.gov/pubmed/32687836 https://doi.org/10.1016/j.neuropsychologia.2020.107568 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534039/
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Mapping Human Laryngeal Motor Cortex during Vocalization
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In: Cereb Cortex (2020)
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Morphological and functional variability in central and subcentral motor cortex of the human brain
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In: Brain Struct Funct (2020)
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Data from: The influence of evaluative right/wrong feedback on phonological and semantic processes in word learning ...
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Stage2_Appendix from The influence of evaluative right/wrong feedback on phonological and semantic processes in word learning. ...
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Supplementary material from "The influence of evaluative right/wrong feedback on phonological and semantic processes in word learning" ...
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Supplementary material from "The influence of evaluative right/wrong feedback on phonological and semantic processes in word learning" ...
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Stage2_Appendix from The influence of evaluative right/wrong feedback on phonological and semantic processes in word learning. ...
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Stage2_Appendix from The influence of evaluative right/wrong feedback on phonological and semantic processes in word learning ...
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Supplementary material from "The influence of evaluative right/wrong feedback on phonological and semantic processes in word learning" ...
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