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DIVA predictions about speech in MV ASD (Chenausky et al., 2021) ...
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DIVA predictions about speech in MV ASD (Chenausky et al., 2021) ...
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Is children’s speech development changing? Preliminary evidence from Australian English-speaking 3-year-olds ...
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Is children’s speech development changing? Preliminary evidence from Australian English-speaking 3-year-olds ...
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A Modeling-Guided Case Study of Disordered Speech in Minimally Verbal Children With Autism Spectrum Disorder
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In: Am J Speech Lang Pathol (2021)
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Speech and language phenotype in Phelan-McDermid (22q13.3) syndrome
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In: Eur J Hum Genet (2020)
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Factor Analysis of Signs of Childhood Apraxia of Speech
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In: J Commun Disord (2020)
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Language in 2-year-old children born preterm and term: a cohort study
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Corticobulbar Tract Injury, Oromotor Impairment and Language Plasticity in Adolescents Born Preterm
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Abstract:
Children born preterm are at risk of impairments in oromotor control, with implications for early feeding and speech development. In this study, we aimed to identify (a) neuroanatomical markers of persistent oromotor deficits using diffusion-weighted imaging (DWI) tractography and (b) evidence of compensatory neuroplasticity using functional MRI (fMRI) during a language production task. In a cross-sectional study of 36 adolescents born very preterm (<33 weeks’ gestation) we identified persistent difficulties in oromotor control in 31% of cases, but no clinical diagnoses of speech-sound disorder (e.g., dysarthria, dyspraxia). We used DWI-tractography to examine the microstructure (fractional anisotropy, FA) of the corticospinal and corticobulbar tracts. Compared to the unimpaired group, the oromotor-impaired group showed (i) reduced FA within the dorsal portion of the left corticobulbar tract (containing fibres associated with movements of the lips, tongue, and larynx) and (ii) greater recruitment of right hemisphere language regions on fMRI. We conclude that, despite the development of apparently normal everyday speech, early injury to the corticobulbar tract leads to persistent subclinical problems with voluntary control of the face, lips, jaw, and tongue. Furthermore, we speculate that early speech problems may be ameliorated by cerebral plasticity – in particular, recruitment of right hemisphere language areas.
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Keyword:
Neuroscience
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URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389783/ http://www.ncbi.nlm.nih.gov/pubmed/30837853 https://doi.org/10.3389/fnhum.2019.00045
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Conversational Language in 3-Year-Old Children Born Very Preterm and at Term
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In: J Speech Lang Hear Res (2019)
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A set of regulatory genes co-expressed in embryonic human brain is implicated in disrupted speech development
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In: ISSN: 1359-4184 ; EISSN: 1476-5578 ; Molecular Psychiatry ; https://hal.archives-ouvertes.fr/hal-01726218 ; Molecular Psychiatry, Nature Publishing Group, In press (2018)
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Data resource profile: the Child LAnguage REpository (CLARE)
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Data resource profile: The Child LAnguage REpository (CLARE)
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Appendix -Supplemental material for A systematic review and meta-analysis of the prognosis of language outcomes for individuals with autism spectrum disorder ...
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Appendix -Supplemental material for A systematic review and meta-analysis of the prognosis of language outcomes for individuals with autism spectrum disorder ...
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A systematic review and meta-analysis of the prognosis of language outcomes for individuals with autism spectrum disorder ...
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A systematic review and meta-analysis of the prognosis of language outcomes for individuals with autism spectrum disorder ...
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Appendix -Supplemental material for A systematic review and meta-analysis of the prognosis of language outcomes for individuals with autism spectrum disorder ...
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