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Lifelong bilingualism and mechanisms of neuroprotection in Alzheimer dementia. ...
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Lifelong bilingualism and mechanisms of neuroprotection in Alzheimer dementia.
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The impact of bilingualism on brain reserve and metabolic connectivity in Alzheimer's dementia
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Perani, Daniela; Farsad, Mohsen; Ballarini, Tommaso; Lubian, Francesca; Malpetti, Maura; Fracchetti, Alessandro; Magnani, Giuseppe; March, Albert; Abutalebi, Jubin. - : National Academy of Sciences, 2017
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Abstract:
Recent epidemiological studies report that lifelong bilingualism may delay dementia onset. However, the underlying neural mechanism of these protective effects is largely unknown. Using fluorodeoxyglucose and PET to investigate brain metabolism and neural connectivity in individuals with Alzheimer’s dementia, we unravel the neural mechanism responsible for the bilingual individuals’ ability to cope better with Alzheimer’s dementia. These findings foster the view that lifelong bilingualism contributes to brain cognitive reserve.
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Keyword:
Biological Sciences
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URL: http://www.ncbi.nlm.nih.gov/pubmed/28137833 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320960/ https://doi.org/10.1073/pnas.1610909114
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