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Utilising a systematic review-based approach to create a database of individual participant data for meta- and network meta-analyses: The RELEASE database of aphasia after stroke
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In: Research outputs 2014 to 2021 (2022)
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A Preliminary Report of Network Electroencephalographic Measures in Primary Progressive Apraxia of Speech and Aphasia
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In: Brain Sciences; Volume 12; Issue 3; Pages: 378 (2022)
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Orofacial Muscle Strength across the Dysarthrias
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In: Brain Sciences; Volume 12; Issue 3; Pages: 365 (2022)
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Baseline structural neuroimaging correlates of treatment outcomes in semantic variant primary progressive aphasia ...
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Tractography of supplementary motor area projections in progressive speech apraxia and aphasia
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Valls Carbo, Adrian; Reid, Robert I.; Tosakulwong, Nirubol; Weigand, Stephen D.; Duffy, Joseph R.; Clark, Heather M.; Utianski, Rene L.; Botha, Hugo; Machulda, Mary M.; Strand, Edythe A.; Schwarz, Christopher G.; Jack, Clifford R.; Josephs, Keith A.; Whitwell, Jennifer L.
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In: Neuroimage Clin (2022)
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Abstract:
Progressive apraxia of speech (AOS) is a motor speech disorder affecting the ability to produce phonetically or prosodically normal speech. Progressive AOS can present in isolation or co-occur with agrammatic aphasia and is associated with degeneration of the supplementary motor area. We aimed to assess breakdowns in structural connectivity from the supplementary motor area in patients with any combination of progressive AOS and/or agrammatic aphasia to determine which supplementary motor area tracts are specifically related to these clinical symptoms. Eighty-four patients with progressive AOS or progressive agrammatic aphasia were recruited by the Neurodegenerative Research Group and underwent neurological, speech/language, and neuropsychological testing, as well as 3 T diffusion magnetic resonance imaging. Of the 84 patients, 36 had apraxia of speech in isolation (primary progressive apraxia of speech, PPAOS), 40 had apraxia of speech and agrammatic aphasia (AOS-PAA), and eight had agrammatic aphasia in isolation (progressive agrammatic aphasia, PAA). Tractography was performed to identify 5 distinct tracts connecting to the supplementary motor area. Fractional anisotropy and mean diffusivity were assessed at 10 positions along the length of the tracts to construct tract profiles, and median profiles were calculated for each tract. In a case-control comparison, decreased fractional anisotropy and increased mean diffusivity were observed along the supplementary motor area commissural fibers in all three groups compared to controls. PPAOS also had abnormal diffusion in tracts from the supplementary motor area to the putamen, prefrontal cortex, Broca’s area (frontal aslant tract) and motor cortex, with greatest abnormalities observed closest to the supplementary motor area. The AOS-PAA group showed abnormalities in the same set of tracts, but with greater involvement of the supplementary motor area to prefrontal tract compared to PPAOS. PAA showed abnormalities in the left prefrontal and frontal aslant tracts compared to both other groups, with PAA showing greatest abnormalities furthest from the supplementary motor area. Severity of AOS correlated with tract metrics in the supplementary motor area commissural and motor cortex tracts. Severity of aphasia correlated with the frontal aslant and prefrontal tracts. These findings provide insight into how AOS and agrammatism are differentially related to disrupted diffusivity, with progressive AOS associated with abnormalities close to the supplementary motor area, and the frontal aslant and prefrontal tracts being particularly associated with agrammatic aphasia.
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Regular Article
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URL: https://doi.org/10.1016/j.nicl.2022.102999 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987652/
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A Preliminary Report of Network Electroencephalographic Measures in Primary Progressive Apraxia of Speech and Aphasia
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In: Brain Sci (2022)
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Adopting or Adapting: Open Education Copyright Instruction for Faculty and Staff
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Effects of word familiarity and receptive vocabulary size on speech-in-noise recognition among young adults with normal hearing
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In: PLoS One (2022)
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Do psychological interventions reduce symptoms of depression for patients with bipolar I or II disorder? A meta-analysis
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Orofacial Muscle Strength across the Dysarthrias
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In: Brain Sci (2022)
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Anesthetic Selection for an Awake Craniotomy for a Glioma With Wernicke’s Aphasia: A Case Report
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In: Cureus (2022)
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Evidence for cumulative cultural evolution in bird song
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In: Philos Trans R Soc Lond B Biol Sci (2022)
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Acoustic Properties for the Kazakh Velar and Uvular Distribution
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In: Proceedings of the Workshop on Turkic and Languages in Contact with Turkic; Vol 6 (2021); 5061 ; 2641-3485 (2022)
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Observation of new excited ${B} ^0_{s} $ states
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In: Eur.Phys.J.C ; https://hal.archives-ouvertes.fr/hal-03010999 ; Eur.Phys.J.C, 2021, 81 (7), pp.601. ⟨10.1140/epjc/s10052-021-09305-3⟩ (2021)
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Utilising a systematic review-based approach to create a database of individual participant data for meta- and network meta-analyses: the RELEASE database of aphasia after stroke
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In: ISSN: 0268-7038 ; EISSN: 1464-5041 ; Aphasiology ; https://hal.archives-ouvertes.fr/hal-03528818 ; Aphasiology, Taylor & Francis (Routledge), 2021, ⟨10.1080/02687038.2021.1897081⟩ (2021)
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Predictors of Poststroke Aphasia Recovery: A Systematic Review-Informed Individual Participant Data Meta-Analysis
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In: ISSN: 0039-2499 ; EISSN: 1524-4628 ; Stroke ; https://hal.archives-ouvertes.fr/hal-03277820 ; Stroke, American Heart Association, 2021, 52 (5), pp.1778-1787. ⟨10.1161/strokeaha.120.031162⟩ (2021)
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Corpus, experimental and modeling investigations of cross-linguistic differences in pronoun resolution preferences
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In: ISSN: 2397-1835 ; EISSN: 2397-1835 ; Glossa: a journal of general linguistics (2021-.) ; https://hal.archives-ouvertes.fr/hal-03506513 ; Glossa: a journal of general linguistics (2021-.), Open Library of Humanities, 2021, 6 (1), ⟨10.5334/gjgl.1142⟩ (2021)
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Function words: implications forthe syntax-phonology interface
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In: OCP 18 ; https://hal.archives-ouvertes.fr/hal-03505542 ; OCP 18, Jan 2021, Ibiza, Spain (2021)
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