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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 11 of 11 1 Prevalence and Predictors of Persistent SSD (Wren et al., 2016) ... Wren, Yvonne; Miller, Laura L.; J. Peters, Tim. - : ASHA journals, 2022 BASE Show details 2 Prevalence and Predictors of Persistent SSD (Wren et al., 2016) ... Wren, Yvonne; Miller, Laura L.; J. Peters, Tim. - : ASHA journals, 2022 BASE Show details 3 Characterization of the DYX2 locus on chromosome 6p22 with reading disability, language impairment, and IQ Eicher, John D.; Powers, Natalie R.; Miller, Laura L.. - : Springer Berlin Heidelberg, 2014 BASE Show details 4 Speech characteristics of 8-year-old children: Findings from a prospective population study Wren, Yvonne; McLeod, Sharynne; White, Paul... In: Journal of communication disorders. - New York, NY : Elsevier 46 (2013) 1, 53-69 OLC Linguistik Show details 5 Associations of Prenatal Nicotine Exposure and the Dopamine Related Genes ANKK1 and DRD2 to Verbal Language Eicher, John D.; Powers, Natalie R.; Cho, Kelly; Miller, Laura L.; Mueller, Kathryn L.; Ring, Susan M.; Tomblin, J. Bruce; Gruen, Jeffrey R.. - : Public Library of Science, 2013 Abstract: Language impairment (LI) and reading disability (RD) are common pediatric neurobehavioral disorders that frequently co-occur, suggesting they share etiological determinants. Recently, our group identified prenatal nicotine exposure as a factor for RD and poor reading performance. Using smoking questionnaire and language data from the Avon Longitudinal Study of Parents and Children, we first determined if this risk could be expanded to other communication disorders by evaluating whether prenatal nicotine exposure increases risk for LI and poor performance on language tasks. Prenatal nicotine exposure increased LI risk (OR = 1.60; p = 0.0305) in a dose-response fashion with low (OR = 1.25; p = 0.1202) and high (OR = 3.84; p = 0.0002) exposures. Next, hypothesizing that the effects of prenatal nicotine may also implicate genes that function in nicotine related pathways, we determined whether known nicotine dependence (ND) genes associate with performance on language tasks. We assessed the association of 33 variants previously implicated in ND with LI and language abilities, finding association between ANKK1/DRD2 and performance on language tasks (p≤0.0003). The associations of markers within ANKK1 were replicated in a separate LI case-control cohort (p<0.05). Our results show that smoking during pregnancy increases the risk for LI and poor performance on language tasks and that ANKK1/DRD2 contributes to language performance. More precisely, these findings suggest that prenatal environmental factors influence in utero development of neural circuits vital to language. Our association of ANKK1/DRD2 further implicates the role of nicotine-related pathways and dopamine signaling in language processing, particularly in comprehension and phonological memory. ; Version of Record Keyword: Behavioral Neuroscience; Biology; Clinical Research Design; Complex Traits; Developmental and Pediatric Neurology; Genetic Association Studies; Genetics; Heredity; Human Genetics; Medicine; Neurology; Neuropsychology; Neuroscience; Pediatrics; Survey Research URL: https://doi.org/10.1371/journal.pone.0063762 http://nrs.harvard.edu/urn-3:HUL.InstRepos:11181191 BASE Hide details 6 Associations of Prenatal Nicotine Exposure and the Dopamine Related Genes ANKK1 and DRD2 to Verbal Language Eicher, John D.; Powers, Natalie R.; Cho, Kelly. - : Public Library of Science, 2013 BASE Show details 7 Distinguishing groups of children with persistent speech disorder: Findings from a prospective population study Wren, Yvonne E.; Roulstone, Sue E.; Miller, Laura L. In: Logopedics, phoniatrics, vocology. - London : Informa Healthcare 37 (2012) 1, 1-10 OLC Linguistik Show details 8 The natural history of speech impairment of 8-year-old children in the Avon Longitudinal Study of Parents and Children: error rates at 2 and 5 years Peters, Tim J.; Wren, Yvonne; Miller, Laura L.... In: International journal of speech language pathology. - Abingdon : Informa Healthcare 11 (2009) 5, 381-391 BLLDB OLC Linguistik Show details 9 CMIP and ATP2C2 Modulate Phonological Short-Term Memory in Language Impairment Ragoussis, Jiannis; Everitt, Andrea; Addis, L.. - 2009 BASE Show details 10 CMIP and ATP2C2 Modulate Phonological Short-Term Memory in Language Impairment Newbury, Dianne F.; Winchester, Laura; Addis, Laura. - : Elsevier, 2009 BASE Show details 11 CMIP and ATP2C2 modulate phonological short-term memory in language impairment Simonoff, Emily; Goodyer, Ian M.; Bolton, Patrick F.. - 2009 BASE Show details

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