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What's "up"? Impaired Spatial Preposition Processing in Posterior Cortical Atrophy.
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Abstract:
This study seeks to confirm whether lesions in posterior regions of the brain involved in visuo-spatial processing are of functional relevance to the processing of words with spatial meaning. We investigated whether patients with Posterior Cortical Atrophy (PCA), an atypical form of Alzheimer's Disease which predominantly affects parieto-occipital brain regions, is associated with deficits in working memory for spatial prepositions. Case series of patients with PCA and matched healthy controls performed tests of immediate and delayed serial recall on words from three lexico-semantic word categories: number words (twelve), spatial prepositions (behind) and function words (e.g., shall). The three word categories were closely matched for a number of psycholinguistic and semantic variables including length, bi-/tri-gram frequency, word frequency, valence and arousal. Relative to controls, memory performance of PCA patients on short word lists was significantly impaired on spatial prepositions in the delayed serial recall task. These results suggest that lesions in posterior parieto-occipital regions specifically impair the processing of spatial prepositions. Our findings point to a pertinent role of posterior cortical regions in the semantic processing of words with spatial meaning and provide strong support for modality-specific semantic theories that recognize the necessary contributions of sensorimotor regions to conceptual semantic processing.
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Keyword:
category specific impairments; embodiment cognition; Human Neuroscience; PCA; posterior cortical atrophy; semantic processing; spatial language processing; spatial prepositions; working memory
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URL: https://doi.org/10.17863/CAM.79428 https://www.repository.cam.ac.uk/handle/1810/331980
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Fostering Transnational, Multilingual Collaboration: The Berlin-based Artists' Initiative WeiterSchreiben.jetzt
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In: TRANSIT, vol 13, iss 1 (2021)
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What's "up"? Impaired Spatial Preposition Processing in Posterior Cortical Atrophy. ...
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Flexible Use of Spatial Frames of Reference for Object–Location Memory in Older Adults
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In: Brain Sciences ; Volume 11 ; Issue 11 (2021)
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A Critical Review of Spatial Abilities in Down and Williams Syndromes: Not All Space Is Created Equal.
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In: Frontiers in psychiatry, vol. 12, pp. 669320 (2021)
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8 |
Lower verbalizability of visual stimuli modulates differences in estimates of working memory capacity between children with and without developmental language disorders
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In: ISSN: 2396-9415 ; Autism & Developmental Language Impairments ; https://hal.archives-ouvertes.fr/hal-02929714 ; Autism & Developmental Language Impairments, 2020, 5, pp.239694152094551. ⟨10.1177/2396941520945519⟩ (2020)
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Validation of a simple screening test for elementary visuo-spatial perception deficit
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In: ISSN: 1877-0657 ; Annals of Physical and Rehabilitation Medicine ; https://hal.archives-ouvertes.fr/hal-03034722 ; Annals of Physical and Rehabilitation Medicine, Elsevier Masson, 2020, 63 (4), pp.302 - 308. ⟨10.1016/j.rehab.2019.03.006⟩ (2020)
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Spatial Language, Spatial Memory and Spatial Perspective Taking in Japanese and English ...
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Spatial Language, Spatial Memory and Spatial Perspective Taking in Japanese and English ...
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Double trouble – visual and phonological impairments in English dyslexic readers
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Spatial memory in Huntington's disease: A comparative review of human and animal data.
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Spatial Language, Spatial Memory and Spatial Perspective Taking in Japanese and English ...
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Natural user interfaces and smart devices for the assessment of spatial memory using auditory stimuli
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Visuospatial Cognition, Movement, and the Mathematic Achievement of Students
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In: Hilton, Courtney. (2018). Visuospatial Cognition, Movement, and the Mathematic Achievement of Students. UC Riverside: Education. Retrieved from: http://www.escholarship.org/uc/item/6ff0z587 (2018)
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18 |
Selection of macroreference frames in spatial memory
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In: Psychology Publications (2018)
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Лексические показатели развития речи у дошкольников с разным уровнем саморегуляции ... : Lexical Indicators of Speech Development in Preschool Children with Different Levels of Self-Regulation ...
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Influence of early-life nutritional stress on songbird memory formation
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