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What is involved and what is necessary for complex linguistic and nonlinguistic auditory processing: evidence from functional magnetic resonance imaging and lesion data
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What is involved and what is necessary for complex linguistic and nonlinguistic auditory processing: evidence from functional magnetic resonance imaging and lesion data
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In: Journal of Cognitive Neuroscience , 19 (5) pp. 799-816. (2007) (2007)
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Lesion correlates of conversational speech production deficits
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In: Neuropsychologia , 45 (11) pp. 2525-2533. (2007) (2007)
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Abstract:
We assess brain areas involved in speech production using a recently developed lesion?symptom mapping method (voxel-based lesion?symptommapping, VLSM) with 50 aphasic patients with left-hemisphere lesions. Conversational speech was collected through a standardized biographicalinterview, and used to determine mean length of utterance in morphemes (MLU), type token ratio (TTR) and overall tokens spoken for each patient.These metrics are used as indicators of grammatical complexity, semantic variation, and amount of speech, respectively. VLSM analysis revealedthat damage to the anterior insula was predictive of low scores on MLU and tokens, consistent with prior findings of the role of this region inspeech production [Dronkers, N. F. (1996). A new brain region for coordinating speech articulation. Nature, 384(6605), 159?161]. Additionally,the inferior frontal gyrus, sensorimotor and anterior temporal areas were also associated with lower scores on both of these measures. Overall,token and MLU maps were highly similar, suggesting an overlap between grammatical language networks and overall fluency. TTR maps alsoshared some portions of this network, but damage to posterior temporal regions also reduced scores on this measure. These results represent thefirst voxel-based lesion analysis of speech production performance in aphasic patients.
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URL: http://discovery.ucl.ac.uk/3669/
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An on-line task for contrasting auditory processing in the verbal and nonverbal domains and norms for younger and older adults
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Analyzing aphasia data in a multidimensional symptom space
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In: Brain and Language , 92 (2) pp.106 - 116. (2005) (2005)
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In search of Noun-Verb dissociations in aphasia across three processing tasks
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In: Center for Research in Language Newsletter , 17 (1) pp.3 - 17. (2005) (2005)
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In search of Noun-Verb dissociations in aphasia across three processing tasks
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In: Center for Research in Language Newsletter , 17 (1) pp.3 - 17. (2005) (2005)
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Analyzing aphasia data in a multidimensional symptom space
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In: Brain and Language , 92 (2) pp.106 - 116. (2005) (2005)
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An online task for contrasting auditory processing in the verbal and nonverbal domains and norms for younger and older adults.
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In: Behavior Research Methods , 37 (1) pp. 99-110. (2005) (2005)
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The development of complex sentence interpretation in typically developing children compared with children with specific language impairments or early unilateral focal lesions
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Action comprehension in aphasia
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In: Neuropsychologia , 42 (13) pp.1788 - 1804. (2004) (2004)
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Action comprehension in aphasia
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In: Neuropsychologia , 42 (13) pp.1788 - 1804. (2004) (2004)
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Neural resources for processing language and environmental sounds: evidence from aphasia
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