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Regional brain volumes, microstructure and neurodevelopment in moderate-late preterm children
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Language in 2-year-old children born preterm and term: a cohort study
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Conversational Language in 3-Year-Old Children Born Very Preterm and at Term
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In: J Speech Lang Hear Res (2019)
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The relationship between ventricular size at 1 month and outcome at 2 years in infants less than 30 weeks' gestation
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General movements in very preterm children and neurodevelopment at 2 and 4 years
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In: Pediatrics, Vol. 132, no. 2 (Aug 2013), pp. E452-E458 (2013)
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Abstract:
OBJECTIVE: Although similar to 50% of very preterm (VP) children have neurodevelopmental impairments, early prediction of infants who will experience problems later in life remains a challenge. This study evaluated the predictive value of general movements (GM; spontaneous and endogenous movements) at 1 and 3 months' corrected age for neurodevelopment at 2 and 4 years of age in VP children. METHODS: At 1 and 3 months' corrected age, infants born,30 weeks' gestation had GM assessed as normal or abnormal. Motor, cognitive, and language development at 2 years was assessed by using the Bayley Scales of Infant and Toddler Development, Third Edition. At 4 years, cognitive and language outcomes were assessed by using the Differential Ability Scale-Second Edition and motor outcomes with the Movement Assessment Battery for Children-Second Edition; a diagnosis of cerebral palsy was documented. RESULTS: Ninety-nine VP infants were recruited, with 97% and 88% of survivors followed up at age 2 and 4 years, respectively. Abnormal GM at 1 month were associated with worse motor outcomes at 2 and 4 years but not language or cognitive outcomes. Abnormal GM at 3 months were associated with worse motor, cognitive, and language outcomes at both 2 and 4 years. Overall, GM at 1 month demonstrated better sensitivity to impairments at 2 and 4 years, whereas GM at 3 months had better specificity and were more accurate overall at distinguishing between children with and without impairment. CONCLUSIONS: Abnormal GM in VP infants, particularly at 3 months postterm, are predictive of worse neurodevelopment at ages 2 and 4 years.
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URL: https://doi.org/10.1542/peds.2013-0177 http://hdl.handle.net/1959.3/366635
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General Movements in Very Preterm Children and Neurodevelopment at 2 and 4 Years
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