| 1 |
Efficient localization of the cortical language network and its functional neuroanatomy in dyslexia
|
|
|
|
Abstract:
The functional neuroanatomy of language localization in dyslexia has primarily been studied in the context of reading. However, dyslexia is sometimes referred to as a “language-based learning disability,” yet the functional signature of the core language comprehension network in dyslexia is far less understood. This thesis presents a series of studies designed to compare the functionality of the brain regions supporting linguistic processing between typical and impaired readers in order to characterize the cortical language network in dyslexia. First, we investigate the extent to which the efficiency (or quality of data vs. amount of scan time) of a functional language localizer based on passive spoken language comprehension can be maximized in Chapter 2. By demarcating the language network based on smaller amounts of data and testing stability and reliability within this framework, we found that scan time can be substantially reduced without sacrificing functional specialization for language. In Chapter 3, we apply the spoken language localizer to determine differences in functional organization of language in dyslexia and provide evidence that the core spoken language comprehension network is not markedly different between typical readers and those with dyslexia. We compared the individual activations from whole-brain analysis and functional profiles in the canonical language-selective regions and found that the functional response of localized language regions in individuals with dyslexia was as selective as in typically reading adults. Chapter 4 follows up on the functional evidence reported in Chapter 3 to examine the structural connectivity within the same functional language network and additionally found essentially no differences between controls and dyslexia, further supporting the observations made in Chapter 3 that core linguistic processing is intact in dyslexia. All together, these findings converge on the suggestion that individuals with dyslexia do not rely on a separate cognitive architecture for language, potentially revealing important new insight into the dissociation of language specialization abilities and reading difficulty in dyslexia.
|
|
Keyword:
Cognition; DWI; fMRI; Language; Neuroimaging; Speech; Test-retest reliability
|
|
URL: https://hdl.handle.net/2144/43724
|
|
BASE
|
|
Hide details
|
|
|
| 2 |
Understanding teachers’ experiences in transitioning from a reading test preparation approach to a whole novel approach : a narrative case study.
|
|
|
|
BASE
|
|
Show details
|
|
|
| 3 |
Development and diagnostic validation of the Brisbane Evidence-Based Language Test
|
|
|
|
In: Research outputs 2014 to 2021 (2022)
|
|
BASE
|
|
Show details
|
|
|
| 4 |
Inter-rater reliability, intra-rater reliability and internal consistency of the Brisbane Evidence-Based Language Test
|
|
|
|
In: Research outputs 2014 to 2021 (2022)
|
|
BASE
|
|
Show details
|
|
|
| 5 |
Repository of psychological instruments in Serbian [Repozitorijum psiholoških instrumenata na srpskom jeziku] (REPOPSI) ...
|
|
|
|
BASE
|
|
Show details
|
|
|
| 6 |
Using Automatic Speech Recognition to Assess Thai Speech Language Fluency in the Montreal Cognitive Assessment (MoCA)
|
|
|
|
In: Sensors; Volume 22; Issue 4; Pages: 1583 (2022)
|
|
BASE
|
|
Show details
|
|
|
| 7 |
Towards a Sustainable Multidimensional Approach to English Proficiency Proof in the Post-Pandemic Era: Learning from the Legacy of COVID-19
|
|
|
|
In: Sustainability; Volume 14; Issue 9; Pages: 5568 (2022)
|
|
BASE
|
|
Show details
|
|
|
| 8 |
Examining English Ability-Grouping Practices by Aligning CEFR Levels with University-Level General English Courses in Taiwan
|
|
|
|
In: Sustainability; Volume 14; Issue 8; Pages: 4629 (2022)
|
|
BASE
|
|
Show details
|
|
|
| 9 |
Reasons behind Low Cervical Screening Uptake among South Asian Immigrant Women: A Qualitative Exploration
|
|
|
|
In: International Journal of Environmental Research and Public Health; Volume 19; Issue 3; Pages: 1527 (2022)
|
|
BASE
|
|
Show details
|
|
|
| 10 |
Developing Resilience to Disinformation: A Game-Based Method for Future Communicators
|
|
|
|
In: Sustainability; Volume 14; Issue 9; Pages: 5438 (2022)
|
|
BASE
|
|
Show details
|
|
|
| 11 |
On the Difference of Scoring in Speech in Babble Tests
|
|
|
|
In: Healthcare; Volume 10; Issue 3; Pages: 458 (2022)
|
|
BASE
|
|
Show details
|
|
|
| 12 |
Correlation between Language Development and Motor Skills, Physical Activity, and Leisure Time Behaviour in Preschool-Aged Children
|
|
|
|
In: Children; Volume 9; Issue 3; Pages: 431 (2022)
|
|
BASE
|
|
Show details
|
|
|
| 13 |
Overall, a Good Test, but…—Swedish Lower Secondary Teachers’ Perceptions and Use of National Test Results of English
|
|
|
|
In: Languages; Volume 7; Issue 1; Pages: 64 (2022)
|
|
BASE
|
|
Show details
|
|
|
| 14 |
Evaluating Perceptions towards the Consequential Validity of Integrated Language Proficiency Assessment
|
|
|
|
In: Languages; Volume 7; Issue 1; Pages: 65 (2022)
|
|
BASE
|
|
Show details
|
|
|
| 15 |
Matching EFL learners with appropriate levels of reading materials : Backing for using Extensive Reading Placement/Progress Test ; EFL学習者の言語能力レベルに適した多読マテリアル : EPERテストの妥当性研究
|
|
|
|
BASE
|
|
Show details
|
|
|
| 16 |
Text+: Language- and text-based Research Data Infrastructure ...
|
|
|
|
BASE
|
|
Show details
|
|
|
| 17 |
Text+: Language- and text-based Research Data Infrastructure ...
|
|
|
|
BASE
|
|
Show details
|
|
|
| 18 |
Text+: Language- and text-based Research Data Infrastructure ...
|
|
|
|
BASE
|
|
Show details
|
|
|
| 19 |
Les adverbes prépositionnels en français au Québec (Saguenay – Lac- St-Jean) : questionnaire comportant 47 fiches ...
|
|
|
|
BASE
|
|
Show details
|
|
|
| 20 |
Les adverbes prépositionnels en français au Québec (Saguenay – Lac- St-Jean) : questionnaire comportant 47 fiches ...
|
|
|
|
BASE
|
|
Show details
|
|
|
|
|
