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A Complementary Joint Training Approach Using Unpaired Speech and Text for Low-Resource Automatic Speech Recognition ...
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Functional maps of direct electrical stimulation-induced speech arrest and anomia: a multicentre retrospective study.
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In: Brain : a journal of neurology, vol 144, iss 8 (2021)
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The representation of variable tone sandhi patterns in Shanghai Wu
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In: Laboratory Phonology: Journal of the Association for Laboratory Phonology; Vol 12, No 1 (2021); 15 ; 1868-6354 (2021)
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Tracing Text Provenance via Context-Aware Lexical Substitution ...
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Fixel-based evidence of microstructural damage in crossing pathways improves language mapping in Post-stroke aphasia
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Zhang, Jie; Zheng, Weihao; Shang, Desheng; Chen, Yating; Zhong, Shuchang; Ye, Jing; Li, Lingling; Yu, Yamei; Zhang, Li; Cheng, Ruidong; He, Fangping; Wu, Dan; Ye, Xiangming; Luo, Benyan
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In: Neuroimage Clin (2021)
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Abstract:
BACKGROUND: The complex crossing-fiber characteristics in the dual-stream system have been ignored by traditional diffusion tensor models regarding disconnections in post-stroke aphasia. It is valuable to identify microstructural damage of crossing-fiber pathways and reveal accurate fiber-specific language mapping in patients with aphasia. METHODS: This cross-sectional study collected magnetic resonance imaging data from 29 participants with post-stroke aphasia in the subacute stage and from 33 age- and sex-matched healthy controls. Fixel-based analysis was performed to examine microstructural fiber density (FD) and bundle cross-section alterations of specific fiber populations in crossing-fiber regions. Group comparisons were performed, and relationships with language scores were assessed. RESULTS: The aphasic group exhibited significant fixel-wise FD reductions in the dual-stream tracts, including the left inferior fronto-occipital fasciculus (IFOF), arcuate fasciculus, and superior longitudinal fasciculus (SLF) III (family-wise-error-corrected p < 0.05). Voxel- and fixel-wise comparisons revealed mismatched distributions in regions with crossing-fiber nexuses. Fixel-wise correlation analyses revealed significant associations between comprehension impairment and reduced FD in the temporal and frontal segments of the left IFOF, and also mapped naming ability to the IFOF. Average features along the whole course of dominant tracts assessed with tract-wise analyses attributed word-level comprehension to the IFOF (r = 0.723, p < 0.001) and revealed a trend-level correlation between sentence-level comprehension and FD of the SLF III (r = 0.451, p = 0.021). The mean FD of the uncinate fasciculus (UF) and IFOF correlated with total and picture naming scores, and the IFOF also correlated with responsive naming subdomains (Bonferroni corrected p < 0.05). CONCLUSIONS: FD reductions of dual streams suggest that intra-axonal volume reduction constitutes the microstructural damage of white matter integrity in post-stroke aphasia. Fixel-based analysis provides a complementary method of language mapping that identifies fiber-specific tracts in the left hemisphere language network with greater specificity than voxel-based analysis. It precisely locates the precise segments of the IFOF for comprehension, yields fiber-specific evidence for the debated UF-naming association, and reveals dissociative subdomain associations with distinct tracts.
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Keyword:
Regular Article
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URL: https://doi.org/10.1016/j.nicl.2021.102774
http://www.ncbi.nlm.nih.gov/pubmed/34371239
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358698/
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Electrophysiological Signatures of Perceiving Alternated Tone in Mandarin Chinese: Mismatch Negativity to Underlying Tone Conflict
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In: Front Psychol (2021)
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The Evaluation Model of College Students' Mental Health in the Environment of Independent Entrepreneurship Using Neural Network Technology
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In: J Healthc Eng (2021)
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Functional maps of direct electrical stimulation-induced speech arrest and anomia: a multicentre retrospective study
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In: Brain (2021)
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Where is the speech production area? Evidence from direct cortical electrical stimulation mapping
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In: Brain (2021)
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The genetic determinants of language network dysconnectivity in drug-naïve early stage schizophrenia
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In: Brain and Mind Institute Researchers' Publications (2021)
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The genetic determinants of language network dysconnectivity in drug-naïve early stage schizophrenia
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In: Brain and Mind Institute Researchers' Publications (2021)
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The genetic determinants of language network dysconnectivity in drug-naïve early stage schizophrenia
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Linguistic diversity in a time of crisis: Language challenges of the COVID-19 pandemic. - Multilingua : Linguistic diversity in a time of crisis: Language challenges of the COVID-19 pandemic. -
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IDS Mannheim
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A Corpus-Based Investigation of Manner/State Complement Constructions in Mandarin Chinese ...
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Chinese postgraduate taught students' transitional experience in the UK: the role of social connections
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The /n/-/ŋ/ Asymmetry upon /ɻ/-Suffixation in Beijing and Elsewhere -- A Phonetically Based OT Analysis
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In: North East Linguistics Society (2020)
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Phonetic Duration Effects on Contour Tone Distribution
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In: North East Linguistics Society (2020)
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Poetry Translation From the Perspective of Creative Treason: Based on the Analysis of Xu Yuanzhong’s Translation of Spring View
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In: Cross-Cultural Communication; Vol 16, No 2 (2020): Cross-Cultural Communication; 64-68 ; 1923-6700 ; 1712-8358 (2020)
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