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Syntactic and Semantic Specialization and Integration in 5- to 6-Year-Old Children during Auditory Sentence Processing
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Family-based genetic investigation of SLI (Andres et al., 2020) ...
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Family-based genetic investigation of SLI (Andres et al., 2020) ...
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2019 ASHA Research Symposium: Mabel L. Rice, Panel Discussion on Specific Language Impairment ...
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2019 ASHA Research Symposium: Mabel L. Rice, What Studies of Twins Tell Us About Specific Language Impairment in Children: Twinning Effects & Heritability at 2, 4, 6, and 16 Years of Age ...
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2019 ASHA Research Symposium: Mabel L. Rice, Panel Discussion on Specific Language Impairment ...
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2019 ASHA Research Symposium: Mabel L. Rice, Panel Discussion on Specific Language Impairment ...
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2019 ASHA Research Symposium: Mabel L. Rice, What Studies of Twins Tell Us About Specific Language Impairment in Children: Twinning Effects & Heritability at 2, 4, 6, and 16 Years of Age ...
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2019 ASHA Research Symposium: Mabel L. Rice, What Studies of Twins Tell Us About Specific Language Impairment in Children: Twinning Effects & Heritability at 2, 4, 6, and 16 Years of Age ...
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Causal Pathways for Specific Language Impairment: Lessons From Studies of Twins
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In: J Speech Lang Hear Res (2020)
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Pedigree-Based Gene Mapping Supports Previous Loci and Reveals Novel Suggestive Loci in Specific Language Impairment
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In: J Speech Lang Hear Res (2020)
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Advances in Specific Language Impairment Research and Intervention: An Overview of Five Research Symposium Papers
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In: J Speech Lang Hear Res (2020)
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Heritability of Specific Language Impairment and Nonspecific Language Impairment at Ages 4 and 6 Years Across Phenotypes of Speech, Language, and Nonverbal Cognition
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In: J Speech Lang Hear Res (2020)
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Birth Prevalence of Congenital Cytomegalovirus Infection in HIV-Exposed Uninfected Children in the Era of Combination Antiretroviral Therapy
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In: J Pediatr (2019)
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Prenatal and perinatal risks for late language emergence in a population-level sample of twins at age 2
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Abstract:
This work is licensed under a Creative Commons Attribution 4.0 International License. ; Background Late Language Emergence (LLE) in the first two years of life is one of the most common parental concerns about child development and reasons for seeking advice from health professionals. LLE is much more prevalent in twins (38%) than singletons (20%). In studies of language development in twins without overt disability, adverse prenatal and perinatal environments have been reported to play a lesser role in the etiology of LLE than adverse postnatal environments. However, there is a lack of population-level evidence about prenatal and perinatal risk factors for LLE in twins. This study investigated the extent to which prenatal and perinatal risk factors were associated with LLE in a population-level sample of twins at age 2 without overt disability. Methods The sample comprised 473 twin pairs drawn from a population sample frame comprising statutory notifications of all births in Western Australia (WA), 2000–2003. Twin pairs in which either twin had a known developmental disorder or exposure to language(s) other than English were excluded. Of the 946 twins, 47.9% were male. There were 313 dizygotic and 160 monozygotic twin pairs. LLE was defined as a score at or below the gender-specific 10th percentile on the MacArthur Communicative Development Inventories: Words and Sentences (CDI-WS) (Words Produced). Bivariate and multivariable logistic regression was used to investigate risk factors associated with LLE. Results In the multivariable model, risk factors for LLE in order of decreasing magnitude were: Gestational diabetes had an adjusted odds ratio (aOR) of 19.5 (95% confidence interval (CI) 1.2, 313.1); prolonged TSR (aOR: 13.6 [2.0, 91.1]); multiparity (aOR: 7.6 [1.6, 37.5]), monozygosity (aOR: 6.9 [1.7, 27.9]) and fetal growth restriction (aOR: 4.6 [1.7, 12.7]). Sociodemographic risk factors (e.g., low maternal education, socioeconomic area disadvantage) were not associated with increased odds of LLE. Conclusions The results suggest that adverse prenatal and perinatal environments are important in the etiology of LLE in twins at age 2. It is important that health professionals discuss twin pregnancy and birth risks for delayed speech and language milestones with parents and provide ongoing developmental monitoring for all twins, not just twins with overt disability.
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Keyword:
Australia; Child development; Language; Late language emergence; Twins
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URL: https://doi.org/10.1186/s12887-018-1035-9 http://hdl.handle.net/1808/29829
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Grammar Clinical Marker Yields Substantial Heritability for Language Impairments in 16-Year-Old Twins
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Risk for Speech and Language Impairments in Pre-school Aged HIV-Exposed Uninfected Children with in utero Combination Antiretroviral Exposure
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Mapping Chromosomal Loci in Specific Language Impairment: A Pedigree-Focused Approach
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Effects of Language Context on Ratings of Shy and Unsociable Behaviors in English Language Learning Children
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