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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 Hits 1 – 20 of 34 1 Computational chemoproteomics to understand the role of selected psychoactives in treating mental health indications Fine, Jonathan; Lackner, Rachel; Samudrala, Ram; Chopra, Gaurav. - : Nature Publishing Group UK, 2019 Abstract: We have developed the Computational Analysis of Novel Drug Opportunities (CANDO) platform to infer homology of drug behaviour at a proteomic level by constructing and analysing structural compound-proteome interaction signatures of 3,733 compounds with 48,278 proteins in a shotgun manner. We applied the CANDO platform to predict putative therapeutic properties of 428 psychoactive compounds that belong to the phenylethylamine, tryptamine, and cannabinoid chemical classes for treating mental health indications. Our findings indicate that these 428 psychoactives are among the top-ranked predictions for a significant fraction of mental health indications, demonstrating a significant preference for treating such indications over non-mental health indications, relative to randomized controls. Also, we analysed the use of specific tryptamines for the treatment of sleeping disorders, bupropion for substance abuse disorders, and cannabinoids for epilepsy. Our innovative use of the CANDO platform may guide the identification and development of novel therapies for mental health indications and provide an understanding of their causal basis on a detailed mechanistic level. These predictions can be used to provide new leads for preclinical drug development for mental health and other neurological disorders. Keyword: Article URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739337/ http://www.ncbi.nlm.nih.gov/pubmed/31511563 https://doi.org/10.1038/s41598-019-49515-0 BASE Hide details 2 English for landscaping professionals : Lehrbuch für den GaLaBau Fine, Jonathan [Verfasser]. - Berlin : Patzer, 2014 DNB Subject Category Language Show details 3 Second language reflects more psychopathology but compensates the verbal fluency in bilinguals with schizophrenia, Eur Neuropsychopharmacol. 2014;24(Suppl 2):S500 ... Smirnova, Daria; Walters, Joel; Fine, Jonathan. - : Unpublished, 2014 BASE Show details 4 Clause complex manifestation in depression Nagar, Revital; Fine, Jonathan In: Text & talk. - Berlin [u.a.] : Mouton de Gruyter 33 (2013) 4, 595-615 OLC Linguistik Show details 5 Clause complex manifestation in depression Nagar, Revital; Fine, Jonathan In: Text and Talk 33 (2013) 4, 595-615 IDS Bibliografie zur Gesprächsforschung 6 Language in psychiatry. A handbook of clinical practice Fine, Jonathan. - London : Equinox Publishing, 2006 IDS Bibliografie zur Gesprächsforschung Show details 7 Language in psychiatry : a handbook of clinical practice Fine, Jonathan. - London [u.a.] : Equinox, 2006 BLLDB UB Frankfurt Linguistik Show details 8 Gender, genre, and writing style in formal written texts Argamon, Shlomo; Koppel, Moshe; Fine, Jonathan... In: Text. - Berlin [u.a.] : Mouton de Gruyter 23 (2003) 3, 321-346 BLLDB Show details 9 Gender, genre, and writing style in formal written texts Argamon, Shlomo; Koppel, Moshe; Fine, Jonathan... In: Text. - Berlin [u.a.] : Mouton de Gruyter 23 (2003) 3, 321-346 OLC Linguistik Show details 10 On the puzzle of language, pragmatics, and schizophrenia Fine, Jonathan In: Psychological reports. - Los Angeles [u.a.] : SAGE 84 (1999) 1, 84-86 BLLDB Show details 11 Towards understanding and studying cohesion in schizophrenic speech Fine, Jonathan In: Applied psycholinguistics. - Cambridge [u.a.] : Cambridge Univ. Press 16 (1995) 1, 25-41 BLLDB Show details 12 Towards understanding and studying cohesion in schizophrenic speech Fine, Jonathan In: Applied psycholinguistics. - Cambridge [u.a.] : Cambridge Univ. Press 16 (1995) 1, 25-42 OLC Linguistik Show details 13 How language works. Cohesion in formal and nonstandard communication Fine, Jonathan. - Norwood N.J. : Ablex, 1994 IDS Bibliografie zur Gesprächsforschung 14 How language works : cohesion in normal and nonstandard communication Fine, Jonathan. - Norwood, NJ : Ablex Publ., 1994 IDS Mannheim Show details 15 How language works : cohesion in normal and nonstandard communication Fine, Jonathan. - Norwood, N.J. : Ablex Publ. Co., 1993 BLLDB UB Frankfurt Linguistik Show details 16 Functions of probabilities on linguistic systems Fine, Jonathan In: Occasional papers in systemic linguistics. - Nottingham : Univ. 6 (1992), 9-18 BLLDB Show details 17 The static and dynamic choices of responding : toward the process of building social reality by the developmentally disordered Fine, Jonathan In: Functional and systemic linguistics (Berlin, 1991), p. 213-234 MPI für Psycholinguistik Show details 18 The static and dynamic choices of responding : toward the process of building social reality by the developmentally disordered Fine, Jonathan In: Functional and systemic linguistics. - Berlin [u.a.] : Mouton de Gruyter (1991), 213-234 BLLDB Show details 19 The static and dynamic choises of responsing. Toward the process of building social reality by the developmentally disordered Fine, Jonathan In: Functional and systemic linguistics. Approaches and use (1991), 212-234 IDS Bibliografie zur Gesprächsforschung Show details 20 Textual systems : their use in creation and miscalculation of social reality Fine, Jonathan; Bartolucci, Giampiero; Szatmari, Peter In: Word. - Abingdon : Routledge, Taylor & Francis Group 40 (1989) 1-2, 65-79 BLLDB Show details Page: 1 2

Mobile view All Catalogues UB Frankfurt Linguistik 4 IDS Mannheim 2 OLC Linguistik 3 UB Frankfurt Retrokatalog 0 DNB Subject Category Language 1 Institut für Empirische Sprachwissenschaft 0 Leibniz-Centre General Linguistics (ZAS) 0 Bibliographies BLLDB 18 BDSL 0 IDS Bibliografie zur deutschen Grammatik 0 IDS Bibliografie zur Gesprächsforschung 4 IDS Konnektoren im Deutschen 0 IDS Präpositionen im Deutschen 0 IDS OBELEX meta 0 MPI-SHH Linguistics Collection 0 MPI for Psycholinguistics 4 Linked Open Data catalogues Annohub 0 Online resources Link directory 0 Journal directory 0 Database directory 0 Dictionary directory 0 Open access documents BASE 2 Linguistik-Repository 0 IDS Publikationsserver 0 Online dissertations 0 Language Description Heritage 0